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Appl. Sci. 2016, 6(2), 46; doi:10.3390/app6020046

Biomedical Applications of Antibacterial Nanofiber Mats Made of Electrospinning with Wire Electrodes

1
Department of Materials and Textiles, Oriental Institute of Technology, New Taipei City 22061, Taiwan
2
Laboratory of Fiber Application and Manufacturing, Department of Fiber and Composite Materials, Feng Chia University, Taichung City 40724, Taiwan
3
School of Chinese Medicine, China Medical University, Taichung City 40402, Taiwan
4
Department of Fashion Design, Asia University, Taichung City 41354, Taiwan
*
Author to whom correspondence should be addressed.
Academic Editor: Philippe Lambin
Received: 12 December 2015 / Revised: 22 January 2016 / Accepted: 28 January 2016 / Published: 4 February 2016
(This article belongs to the Section Nanotechnology and Applied Nanosciences)
View Full-Text   |   Download PDF [4270 KB, uploaded 4 February 2016]   |  

Abstract

Twisted stainless steel wires are used as wire electrodes for electrospinning the polyvinyl alcohol (PVA)/zinc citrate nanofiber mats. The morphology and diameter of the nanofibers in PVA/zinc citrate nanofiber mats are evaluated. We measured the antibacterial efficacy against Staphylococcus aureus (S. aureus) and Escherichia coli (E. coli) of the nanofiber mats. We also examined the cell adhesion affinity of mammalian tissue culture cells on these nanofiber mats. Our results indicate that an increase in zinc citrate increases the viscosity and electrical conductivity of PVA solution. In addition, increasing zinc citrate results in a smaller diameter of nanofibers that reaches below 100 nm. According to the antibacterial test results, increasing zinc citrate enlarges the inhibition zone of S. aureus but only has a bacteriostatic effect against E. coli. Finally, cell adhesion test results indicate that all nanofiber mats have satisfactory cell attachment regardless of the content of zinc citrate. View Full-Text
Keywords: electrospinning; biomedical applications; blends; ionic Liquids; biomaterials electrospinning; biomedical applications; blends; ionic Liquids; biomaterials
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Pan, Y.-J.; Lin, J.-H.; Chiang, K.-C. Biomedical Applications of Antibacterial Nanofiber Mats Made of Electrospinning with Wire Electrodes. Appl. Sci. 2016, 6, 46.

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