Next Article in Journal
New Programmable CMOS Fuzzifier and C2V Circuits Applicable in FLC Chip for Signal Processing of MEMS Glucose Sensors
Previous Article in Journal
An Investigation of the Thermal Expansion Coefficient for Resin Concrete with ZrW2O8
Article Menu

Export Article

Open AccessReview
Appl. Sci. 2015, 5(3), 380-401; doi:10.3390/app5030380

Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review

Laboratory of Organometallic Compounds and Catalysis (CSIC Associated Unit), Innovation Center in Advanced Chemistry (ORFEO-CINQA), Department of Organic and Inorganic Chemistry, Institute of Organometallic Chemistry "Enrique Moles", Faculty of Chemistry, University of Oviedo, Oviedo E-33006, Spain
Academic Editor: Thomas J. J. Müller
Received: 11 July 2015 / Revised: 6 August 2015 / Accepted: 13 August 2015 / Published: 18 August 2015

Abstract

The air-stable hydride-platinum(II) complex [PtH{(PMe2O)2H}(PMe2OH)], reported by Parkins and co-workers in 1995, is the most versatile catalyst currently available for the hydration of C≡N bonds. It features remarkable activity under relatively mild conditions and exceptionally high functional group compatibility, facts that have allowed the implementation of this complex in the synthesis of a large number of structurally complex, biologically active molecules and natural products. In this contribution, synthetic applications of the Parkins catalyst are reviewed. View Full-Text
Keywords: homogeneous catalysis; hydration reactions; platinum; amides; nitriles; organic synthesis homogeneous catalysis; hydration reactions; platinum; amides; nitriles; organic synthesis
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Cadierno, V. Synthetic Applications of the Parkins Nitrile Hydration Catalyst [PtH{(PMe2O)2H}(PMe2OH)]: A Review. Appl. Sci. 2015, 5, 380-401.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Appl. Sci. EISSN 2076-3417 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top