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Behav. Sci. 2014, 4(2), 125-153; doi:10.3390/bs4020125
Review

Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders

1,* , 1
, 2
 and 1
Received: 6 March 2014; in revised form: 15 May 2014 / Accepted: 21 May 2014 / Published: 13 June 2014
(This article belongs to the Special Issue Management and Treatment of the Major Mental Disorders)
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Abstract: Neurotensin (NT) is a neuropeptide that is closely associated with, and is thought to modulate, dopaminergic and other neurotransmitter systems involved in the pathophysiology of various mental disorders. This review outlines data implicating NT in the pathophysiology and management of major mental disorders such as schizophrenia, drug addiction, and autism. The data suggest that NT receptor analogs have the potential to be used as novel therapeutic agents acting through modulation of neurotransmitter systems dys-regulated in these disorders.
Keywords: neurotensin; schizophrenia; antipsychotic drugs; addiction; autism spectrum disorder; animal models neurotensin; schizophrenia; antipsychotic drugs; addiction; autism spectrum disorder; animal models
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Boules, M.M.; Fredrickson, P.; Muehlmann, A.M.; Richelson, E. Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders. Behav. Sci. 2014, 4, 125-153.

AMA Style

Boules MM, Fredrickson P, Muehlmann AM, Richelson E. Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders. Behavioral Sciences. 2014; 4(2):125-153.

Chicago/Turabian Style

Boules, Mona M.; Fredrickson, Paul; Muehlmann, Amber M.; Richelson, Elliott. 2014. "Elucidating the Role of Neurotensin in the Pathophysiology and Management of Major Mental Disorders." Behav. Sci. 4, no. 2: 125-153.


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