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The Role of Proteomics in Biomarker Development for Improved Patient Diagnosis and Clinical Decision Making in Prostate Cancer
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Diagnostics 2017, 7(1), 6; doi:10.3390/diagnostics7010006

A Promising Future for Prostate Cancer Diagnostics

Discipline of Physiology, School of Biomedical Sciences and Bosch Institute, University of Sydney, Sydney, NSW 2006, Australia
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Author to whom correspondence should be addressed.
Academic Editor: Andreas Kjaer
Received: 30 November 2016 / Revised: 9 January 2017 / Accepted: 11 January 2017 / Published: 17 January 2017
(This article belongs to the Special Issue Prostate Cancer Diagnosis)
View Full-Text   |   Download PDF [175 KB, uploaded 17 January 2017]

Abstract

It has been estimated that globally there is a death attributable to prostate cancer every four minutes. As life expectancy in all world regions increases, so too incidence of this disease of the ageing male will increase. For many men diagnosis occurs after presentation with symptoms of altered urinary dynamics. Unfortunately, these changes, whilst also associated with benign disease, are evident quite late in the aetiology of prostate cancer. Early detection provides for better management and prognosis. This Special Issue provides an up to date view of the advances made towards early diagnosis and prognosis. It provides reviews of advanced imaging techniques (e.g., multiparametric MRI and protocols), and of biomaterials and molecular biomarkers currently being explored (e.g., microRNAs, proteomics) and the technologies that are revolutionizing this field. It describes the multi-disciplinary approaches that are essential to inexpensive, deliverable and accurate platforms for prostate cancer diagnostics. View Full-Text
Keywords: PI-RADS; diffusion weighted imaging; 223RaCl2; [18F]-NaF PET/CT; PERCIST; circulating tumour cells; oncosomes; oncosomal DNAs and RNAs; quantum dot multiplex arrays; carbon nanotube technologies PI-RADS; diffusion weighted imaging; 223RaCl2; [18F]-NaF PET/CT; PERCIST; circulating tumour cells; oncosomes; oncosomal DNAs and RNAs; quantum dot multiplex arrays; carbon nanotube technologies
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Assinder, S.J.; Bhoopalan, V. A Promising Future for Prostate Cancer Diagnostics. Diagnostics 2017, 7, 6.

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