Limitations and Prospects for Diffusion-Weighted MRI of the Prostate
AbstractDiffusion-weighted imaging (DWI) is the most effective component of the modern multi-parametric magnetic resonance imaging (mpMRI) scan for prostate pathology. DWI provides the strongest prediction of cancer volume, and the apparent diffusion coefficient (ADC) correlates moderately with Gleason grade. Notwithstanding the demonstrated cancer assessment value of DWI, the standard measurement and signal analysis methods are based on a model of water diffusion dynamics that is well known to be invalid in human tissue. This review describes the biophysical limitations of the DWI component of the current standard mpMRI protocol and the potential for significantly improved cancer assessment performance based on more sophisticated measurement and signal modeling techniques. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Bourne, R.; Panagiotaki, E. Limitations and Prospects for Diffusion-Weighted MRI of the Prostate. Diagnostics 2016, 6, 21.
Bourne R, Panagiotaki E. Limitations and Prospects for Diffusion-Weighted MRI of the Prostate. Diagnostics. 2016; 6(2):21.Chicago/Turabian Style
Bourne, Roger; Panagiotaki, Eleftheria. 2016. "Limitations and Prospects for Diffusion-Weighted MRI of the Prostate." Diagnostics 6, no. 2: 21.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.