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Diagnostics 2015, 5(4), 577-614; doi:10.3390/diagnostics5040577

Role of Hybrid Brain Imaging in Neuropsychiatric Disorders

1
St. Joseph’s Health Care London, Parkwood Institute, 550 Wellington Road, London, ON N6C 0A7, Canada
2
Department of Psychiatry, Schulich School of Medicine & Dentistry, University of Western Ontario, London, ON N6C 2R6, Canada
3
Lawson Health Research Institute, London, ON N6C 2R5, Canada
These authors contributed equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Andreas Kjaer
Received: 5 October 2015 / Revised: 21 November 2015 / Accepted: 26 November 2015 / Published: 4 December 2015
(This article belongs to the Collection Hybrid Imaging in Medicine)
View Full-Text   |   Download PDF [1753 KB, uploaded 4 December 2015]   |  

Abstract

This is a focused review of imaging literature to scope the utility of hybrid brain imaging in neuropsychiatric disorders. The review focuses on brain imaging modalities that utilize hybrid (fusion) techniques to characterize abnormal brain molecular signals in combination with structural and functional changes that have been observed in neuropsychiatric disorders. An overview of clinical hybrid brain imaging technologies for human use is followed by a selective review of the literature that conceptualizes the use of these technologies in understanding basic mechanisms of major neuropsychiatric disorders and their therapeutics. Neuronal network abnormalities are highlighted throughout this review to scope the utility of hybrid imaging as a potential biomarker for each disorder. View Full-Text
Keywords: neuropsychiatric disorders; neuroimaging; humans; brain disorders/diagnosis; hybrid imaging; molecular imaging; neuronal networks; Alzheimer’s disease; schizophrenia; affective disorders neuropsychiatric disorders; neuroimaging; humans; brain disorders/diagnosis; hybrid imaging; molecular imaging; neuronal networks; Alzheimer’s disease; schizophrenia; affective disorders
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Burhan, A.M.; Marlatt, N.M.; Palaniyappan, L.; Anazodo, U.C.; Prato, F.S. Role of Hybrid Brain Imaging in Neuropsychiatric Disorders. Diagnostics 2015, 5, 577-614.

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