Next Article in Journal
Piecemeal Buildup of the Genetic Code, Ribosomes, and Genomes from Primordial tRNA Building Blocks
Previous Article in Journal
Screening of a Haloferax volcanii Transposon Library Reveals Novel Motility and Adhesion Mutants
Article Menu

Export Article

Open AccessReview
Life 2016, 6(4), 42; doi:10.3390/life6040042

Cyanobacteria as Chassis for Industrial Biotechnology: Progress and Prospects

1
Biology Department, College of Science, Sultan Qaboos University, Al-Khoud, P.O. Box 36, Muscat 123, Oman
2
Institute of Structural & Molecular Biology, University College London, London WC1E 6BT, UK
*
Author to whom correspondence should be addressed.
Academic Editor: David Deamer
Received: 22 August 2016 / Revised: 13 November 2016 / Accepted: 25 November 2016 / Published: 30 November 2016
View Full-Text   |   Download PDF [1065 KB, uploaded 30 November 2016]   |  

Abstract

Cyanobacteria hold significant potential as industrial biotechnology (IB) platforms for the production of a wide variety of bio-products ranging from biofuels such as hydrogen, alcohols and isoprenoids, to high-value bioactive and recombinant proteins. Underpinning this technology, are the recent advances in cyanobacterial “omics” research, the development of improved genetic engineering tools for key species, and the emerging field of cyanobacterial synthetic biology. These approaches enabled the development of elaborate metabolic engineering programs aimed at creating designer strains tailored for different IB applications. In this review, we provide an overview of the current status of the fields of cyanobacterial omics and genetic engineering with specific focus on the current molecular tools and technologies that have been developed in the past five years. The paper concludes by giving insights on future commercial applications of cyanobacteria and highlights the challenges that need to be addressed in order to make cyanobacterial industrial biotechnology more feasible in the near future. View Full-Text
Keywords: cyanobacteria; biotechnology; biofuels; bio-products; genetic engineering cyanobacteria; biotechnology; biofuels; bio-products; genetic engineering
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Al-Haj, L.; Lui, Y.T.; Abed, R.M.; Gomaa, M.A.; Purton, S. Cyanobacteria as Chassis for Industrial Biotechnology: Progress and Prospects. Life 2016, 6, 42.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Life EISSN 2075-1729 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top