Codon Distribution in Error-Detecting Circular Codes
AbstractIn 1957, Francis Crick et al. suggested an ingenious explanation for the process of frame maintenance. The idea was based on the notion of comma-free codes. Although Crick’s hypothesis proved to be wrong, in 1996, Arquès and Michel discovered the existence of a weaker version of such codes in eukaryote and prokaryote genomes, namely the so-called circular codes. Since then, circular code theory has invariably evoked great interest and made significant progress. In this article, the codon distributions in maximal comma-free, maximal self-complementary C3 and maximal self-complementary circular codes are discussed, i.e., we investigate in how many of such codes a given codon participates. As the main (and surprising) result, it is shown that the codons can be separated into very few classes (three, or five, or six) with respect to their frequency. Moreover, the distribution classes can be hierarchically ordered as refinements from maximal comma-free codes via maximal self-complementary C3 codes to maximal self-complementary circular codes. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Fimmel, E.; Strüngmann, L. Codon Distribution in Error-Detecting Circular Codes. Life 2016, 6, 14.
Fimmel E, Strüngmann L. Codon Distribution in Error-Detecting Circular Codes. Life. 2016; 6(1):14.Chicago/Turabian Style
Fimmel, Elena; Strüngmann, Lutz. 2016. "Codon Distribution in Error-Detecting Circular Codes." Life 6, no. 1: 14.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.