Next Article in Journal / Special Issue
Predator Avoidance in Extremophile Fish
Previous Article in Journal / Special Issue
Quorum Sensing in Extreme Environments
Life 2013, 3(1), 149-160; doi:10.3390/life3010149
Review

Periplasmic Binding Proteins in Thermophiles: Characterization and Potential Application of an Arginine-Binding Protein from Thermotoga maritima: A Brief Thermo-Story

1
, 1
, 2
, 1
, 1
 and 1,*
Received: 16 November 2012; in revised form: 11 January 2013 / Accepted: 29 January 2013 / Published: 5 February 2013
(This article belongs to the Special Issue Extremophiles and Extreme Environments)
View Full-Text   |   Download PDF [551 KB, uploaded 5 February 2013]   |   Browse Figures
Abstract: Arginine-binding protein from the extremophile Thermotoga maritima is a 27.7 kDa protein possessing the typical two-domain structure of the periplasmic binding proteins family. The protein is characterized by a very high specificity and affinity to bind to arginine, also at high temperatures. Due to its features, this protein could be taken into account as a potential candidate for the design of a biosensor for arginine. It is important to investigate the stability of proteins when they are used for biotechnological applications. In this article, we review the structural and functional features of an arginine-binding protein from the extremophile Thermotoga maritima with a particular eye on its potential biotechnological applications.
Keywords: ABC transporters; periplasmic binding proteins; arginine; structural stability; unfolding ABC transporters; periplasmic binding proteins; arginine; structural stability; unfolding
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Export to BibTeX |
EndNote


MDPI and ACS Style

Ausili, A.; Staiano, M.; Dattelbaum, J.; Varriale, A.; Capo, A.; D'Auria, S. Periplasmic Binding Proteins in Thermophiles: Characterization and Potential Application of an Arginine-Binding Protein from Thermotoga maritima: A Brief Thermo-Story. Life 2013, 3, 149-160.

AMA Style

Ausili A, Staiano M, Dattelbaum J, Varriale A, Capo A, D'Auria S. Periplasmic Binding Proteins in Thermophiles: Characterization and Potential Application of an Arginine-Binding Protein from Thermotoga maritima: A Brief Thermo-Story. Life. 2013; 3(1):149-160.

Chicago/Turabian Style

Ausili, Alessio; Staiano, Maria; Dattelbaum, Jonathan; Varriale, Antonio; Capo, Alessandro; D'Auria, Sabato. 2013. "Periplasmic Binding Proteins in Thermophiles: Characterization and Potential Application of an Arginine-Binding Protein from Thermotoga maritima: A Brief Thermo-Story." Life 3, no. 1: 149-160.


Life EISSN 2075-1729 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert