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Genes 2017, 8(6), 160; doi:10.3390/genes8060160

Haplotypes of the Ovine Adiponectin Gene and Their Association with Growth and Carcass Traits in New Zealand Romney Lambs

1
Faculty of Wujiang, Tongren University, Tongren 554300, China
2
Gansu Key Laboratory of Herbivorous Animal Biotechnology, Faculty of Animal Science and Technology, Gansu Agricultural University, Lanzhou 730070, China
3
Gene-Marker Laboratory, Faculty of Agriculture and Life Sciences, PO Box 84, Lincoln University, Lincoln 7646, New Zealand
*
Authors to whom correspondence should be addressed.
Academic Editor: J. Peter W. Young
Received: 21 April 2017 / Revised: 26 May 2017 / Accepted: 3 June 2017 / Published: 12 June 2017
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Abstract

Adiponectin plays an important role in energy homeostasis and metabolism in mammalian adipose tissue. In this study, the relationship between adiponectin gene (ADIPOQ) haplotypes and variation in growth and carcass traits in New Zealand (NZ) Romney lambs was investigated using General Linear Models (GLMs). Eight haplotypes were found in these lambs and they were composed of the four previously reported promoter fragment sequences (A1D1) and three previously reported intron 2–exon 3 sequences (A3C3). The frequencies of the haplotypes ranged from 0.07% to 45.91%. The presence of A1A3 was associated with a decreased pre-weaning growth rate (p = 0.037), and decreased leg lean-meat yield (p = 0.001), loin lean-meat yield (p = 0.018) and total lean-meat yield (p = 0.004). The presence of A1C3 was associated with increased carcass fat depth over the 12th rib (V-GR; p = 0.001) and a decreased proportion of loin lean-meat yield (p = 0.045). The presence of B1A3 was associated with an increased proportion of leg lean-meat yield (p = 0.016) and proportion of shoulder lean-meat yield (p = 0.030). No associations were found with birth weight, tailing weight and weaning weight. These results suggest that ovine ADIPOQ may have value as a genetic marker for NZ Romney sheep breeding. View Full-Text
Keywords: adiponectin gene (ADIPOQ); variation; haplotype; growth traits; carcass traits adiponectin gene (ADIPOQ); variation; haplotype; growth traits; carcass traits
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MDPI and ACS Style

An, Q.; Zhou, H.; Hu, J.; Luo, Y.; Hickford, J.G.H. Haplotypes of the Ovine Adiponectin Gene and Their Association with Growth and Carcass Traits in New Zealand Romney Lambs. Genes 2017, 8, 160.

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