Next Article in Journal
Regulation of DNA Replication in Early Embryonic Cleavages
Previous Article in Journal
RNA Editing, ADAR1, and the Innate Immune Response
Article Menu

Export Article

Open AccessArticle
Genes 2017, 8(1), 40; doi:10.3390/genes8010040

Genome Analysis of a Novel Broad Host Range Proteobacteria Phage Isolated from a Bioreactor Treating Industrial Wastewater

1
Avram and Stella Goldstein-Goren Department of Biotechnology Engineering, Ben-Gurion University of the Negev, P.O. Box 653, Be’er Sheva 8410501, Israel
2
Unit of Environmental Engineering, Faculty of Engineering Sciences, Ben-Gurion University of the Negev, Be’er Sheva 8410501, Israel
3
The National Institute for Biotechnology in the Negev, Ben-Gurion University of the Negev, Be’er Sheva 8410501, Israel
4
The Ilse Katz Center for Meso and Nanoscale Science and Technology, Ben-Gurion University of the Negev, Be’er Sheva 8410501, Israel
*
Author to whom correspondence should be addressed.
Academic Editor: Thierry Wirth
Received: 7 August 2016 / Revised: 27 December 2016 / Accepted: 11 January 2017 / Published: 18 January 2017
(This article belongs to the Section Microbial Genetics and Genomics)
View Full-Text   |   Download PDF [3966 KB, uploaded 20 January 2017]   |  

Abstract

Bacteriophages are viruses that infect bacteria, and consequently they have a major impact on the development of a microbial population. In this study, the genome of a novel broad host range bacteriophage, Aquamicrobium phage P14, isolated from a wastewater treatment plant, was analyzed. The Aquamicrobium phage P14 was found to infect members of different Proteobacteria classes (Alphaproteobacteria and Betaproteobacteria). This phage contains a 40,551 bp long genome and 60% of its genes had blastx hits. Furthermore, the bacteriophage was found to share more than 50% of its genes with several podoviruses and has the same gene order as other polyvalent bacteriophages. The results obtained in this study led to the conclusion that indeed general features of the genome of the Aquamicrobium phage P14 are shared with other broad host range bacteriophages, however further analysis of the genome is needed in order to identify the specific mechanisms which enable the bacteriophage to infect both Alphaproteobacteria and Betaproteobacteria. View Full-Text
Keywords: bacteriophage; Aquamicrobium; polyvalent; genome; wastewater bacteriophage; Aquamicrobium; polyvalent; genome; wastewater
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

de Leeuw, M.; Baron, M.; Brenner, A.; Kushmaro, A. Genome Analysis of a Novel Broad Host Range Proteobacteria Phage Isolated from a Bioreactor Treating Industrial Wastewater. Genes 2017, 8, 40.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Genes EISSN 2073-4425 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top