The SaeRS Two‐Component System of Staphylococcus aureus
AbstractIn the Gram‐positive pathogenic bacterium Staphylococcus aureus, the SaeRS twocomponent system (TCS) plays a major role in controlling the production of over 20 virulence factors including hemolysins, leukocidins, superantigens, surface proteins, and proteases. The SaeRS TCS is composed of the sensor histidine kinase SaeS, response regulator SaeR, and two auxiliary proteins SaeP and SaeQ. Since its discovery in 1994, the sae locus has been studied extensively, and its contributions to staphylococcal virulence and pathogenesis have been well documented and understood; however, the molecular mechanism by which the SaeRS TCS receives and processes cognate signals is not. In this article, therefore, we review the literature focusing on the signaling mechanism and its interaction with other global regulators. View Full-Text
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Liu, Q.; Yeo, W.; Bae, T. The SaeRS Two‐Component System of Staphylococcus aureus. Genes 2016, 7, 81.
Liu Q, Yeo W, Bae T. The SaeRS Two‐Component System of Staphylococcus aureus. Genes. 2016; 7(10):81.Chicago/Turabian Style
Liu, Qian; Yeo, Won‐Sik; Bae, Taeok. 2016. "The SaeRS Two‐Component System of Staphylococcus aureus." Genes 7, no. 10: 81.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.