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Revisiting Respect for Persons in Genomic Research
Johns Hopkins Berman Institute of Bioethics, 1809 Ashland Avenue, Baltimore, MD 21205, USA
Department of Health Policy and Management, Johns Hopkins Bloomberg School of Health, 615 North Wolfe St., Baltimore, MD 21205, USA
Division of Neurogenetics, Kennedy Krieger Institute, 801 N. Broadway, Rm. 564, Baltimore, MD 21205, USA
* Author to whom correspondence should be addressed.
Received: 15 November 2013; in revised form: 2 December 2013 / Accepted: 8 January 2014 / Published: 22 January 2014
Abstract: The risks and benefits of research using large databases of personal information are evolving in an era of ubiquitous, internet-based data exchange. In addition, information technology has facilitated a shift in the relationship between individuals and their personal data, enabling increased individual control over how (and how much) personal data are used in research, and by whom. This shift in control has created new opportunities to engage members of the public as partners in the research enterprise on more equal and transparent terms. Here, we consider how some of the technological advances driving and paralleling developments in genomics can also be used to supplement the practice of informed consent with other strategies to ensure that the research process as a whole honors the notion of respect for persons upon which human research subjects protections are premised. Further, we suggest that technological advances can help the research enterprise achieve a more thoroughgoing respect for persons than was possible when current policies governing human subject research were developed. Questions remain about the best way to revise policy to accommodate these changes.
Keywords: respect for persons; genomics; genetics; informed consent
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MDPI and ACS Style
Mathews, D.J.H.; Jamal, L. Revisiting Respect for Persons in Genomic Research. Genes 2014, 5, 1-12.
Mathews DJH, Jamal L. Revisiting Respect for Persons in Genomic Research. Genes. 2014; 5(1):1-12.
Mathews, Debra J.H.; Jamal, Leila. 2014. "Revisiting Respect for Persons in Genomic Research." Genes 5, no. 1: 1-12.