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Genes 2011, 2(1), 131-151; doi:10.3390/genes2010131

Gene Duplication and Ectopic Gene Conversion in Drosophila

Department of Molecular Biology and Genetics, Cornell University, 107 Biotechnology Building, Ithaca, NY 14853, USA
Author to whom correspondence should be addressed.
Received: 24 December 2010 / Revised: 26 January 2011 / Accepted: 27 February 2011 / Published: 11 February 2011
(This article belongs to the Special Issue Gene Conversion in Duplicated Genes)
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The evolutionary impact of gene duplication events has been a theme of Drosophila genetics dating back to the Morgan School. While considerable attention has been placed on the genetic novelties that duplicates are capable of introducing, and the role that positive selection plays in their early stages of duplicate evolution, much less attention has been given to the potential consequences of ectopic (non-allelic) gene conversion on these evolutionary processes. In this paper we consider the historical origins of ectopic gene conversion models and present a synthesis of the current Drosophila data in light of several primary questions in the field.
Keywords: ectopic gene conversion; gene conversion; non-allelic conversion; gene duplication; Drosophila; selection ectopic gene conversion; gene conversion; non-allelic conversion; gene duplication; Drosophila; selection
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Arguello, J.R.; Connallon, T. Gene Duplication and Ectopic Gene Conversion in Drosophila. Genes 2011, 2, 131-151.

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