Cyclic GMP and Cilia Motility
AbstractMotile cilia of the lungs respond to environmental challenges by increasing their ciliary beat frequency in order to enhance mucociliary clearance as a fundamental tenant of innate defense. One important second messenger in transducing the regulable nature of motile cilia is cyclic guanosine 3′,5′-monophosphate (cGMP). In this review, the history of cGMP action is presented and a survey of the existing data addressing cGMP action in ciliary motility is presented. Nitric oxide (NO)-mediated regulation of cGMP in ciliated cells is presented in the context of alcohol-induced cilia function and dysfunction. View Full-Text
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Wyatt, T.A. Cyclic GMP and Cilia Motility. Cells 2015, 4, 315-330.
Wyatt TA. Cyclic GMP and Cilia Motility. Cells. 2015; 4(3):315-330.Chicago/Turabian Style
Wyatt, Todd A. 2015. "Cyclic GMP and Cilia Motility." Cells 4, no. 3: 315-330.