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Polymers 2017, 9(12), 633;

Microwave Assisted Preparation of Antimicrobial Chitosan with Guanidine Oligomers and Its Application in Hygiene Paper Products

State Key Laboratory of Pulp and Paper Engineering, South China University of Technology, Guangzhou 510640, China
Department of Chemical Engineering, University of New Brunswick, Fredericton, NB E3B 5A3, Canada
Author to whom correspondence should be addressed.
Received: 12 October 2017 / Revised: 9 November 2017 / Accepted: 13 November 2017 / Published: 24 November 2017
(This article belongs to the Special Issue Antimicrobial Polymers)
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Guanidinylated chitosan (GCS) was prepared by grafting guanidine oligomers onto chitosan under microwave irradiation. The structure of GCS characterized by FT-IR and 1H NMR verified the covalent bonding between the guanidine oligomers and chitosan; the effects of molar ratio, reaction temperature, and time were investigated and the degree of substitution of GCS reached a maximum of 25.5% under optimized conditions in this work. The resulting GCS showed significantly enhanced antimicrobial activities. The results obtained from the dynamic UV absorption of Escherichia coli (E. coli) and atomic force microscopy (AFM) revealed that the deactivation of E. coli by GCS was due to the destructing of the cell membrane and the prompt release of cytoplasm from the bacterial cells. The adsorption of GCS onto cellulose fibers and the antimicrobial efficiency of the hygiene papers with GCS were also investigated. Microwave irradiation as a green assisted method was applied to promote this reaction. This facile approach allowed chitosan to be guanidinylated without tedious preparation procedures and thus broadened its application as a biocompatible antimicrobial agent. View Full-Text
Keywords: chitosan; guanidine; microwave irradiation; antimicrobial activity; hygiene paper chitosan; guanidine; microwave irradiation; antimicrobial activity; hygiene paper

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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Li, J.; Ye, Y.; Xiao, H.; He, B.; Qian, L. Microwave Assisted Preparation of Antimicrobial Chitosan with Guanidine Oligomers and Its Application in Hygiene Paper Products. Polymers 2017, 9, 633.

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