Next Article in Journal
Evaluation of Electrospun PCL-PIBMD Meshes Modified with Plasmid Complexes in Vitro and in Vivo
Next Article in Special Issue
Polydopamine Particle as a Particulate Emulsifier
Previous Article in Journal
pH-Responsive Intra- and Inter-Molecularly Micelle Formation of Anionic Diblock Copolymer in Water
Previous Article in Special Issue
Initiator Systems Effect on Particle Coagulation and Particle Size Distribution in One-Step Emulsion Polymerization of Styrene
Article Menu

Export Article

Open AccessArticle
Polymers 2016, 8(3), 53; doi:10.3390/polym8030053

Improved Stability of Emulsions in Preparation of Uniform Small-Sized Konjac Glucomanna (KGM) Microspheres with Epoxy-Based Polymer Membrane by Premix Membrane Emulsification

1
National Key Laboratory of Biochemical Engineering , Institute of Process Engineering, Chinese Academy of Sciences, Beijing 100190, China
2
University of Chinese Academy of Sciences, Beijing 100049, China
These authors contribute equally to this work.
*
Author to whom correspondence should be addressed.
Academic Editor: Francoise M. Winnik
Received: 26 January 2016 / Revised: 9 February 2016 / Accepted: 16 February 2016 / Published: 23 February 2016
(This article belongs to the Special Issue Selected Papers from ASEPFPM2015)
View Full-Text   |   Download PDF [6474 KB, uploaded 23 February 2016]   |  

Abstract

Uniform small-sized (<10 μm) Konjac glucomanna (KGM) microspheres have great application prospects in bio-separation, drug delivery and controlled release. Premix membrane emulsification is an effective method to prepare uniform small-sized KGM microspheres. However, since KGM solution bears strong alkalinity, it requires the membrane to have a hydrophobic surface resistant to alkali. In this study, uniform small-sized KGM microspheres were prepared with epoxy-based polymer membrane (EP) we developed by premix membrane emulsification. It was found that emulsion coalescence and flocculation occurred frequently due to the high interface energy and sedimentation velocity of KGM emulsions. Emulsion stability had a significant influence on the uniformity and dispersity of the final KGM microspheres. To improve the stability of the emulsions, the effects of the concentration of the emulsifier, the viscosity of the KGM solution, the oil phase composition and the feeding method of epoxy chloropropane (EC) on the preparation results were studied. Under optimal preparation conditions (emulsifier 5 wt % PO-5s, KGM III (145.6 mPa·s), weight ratio of liquid paraffin (LP) to petroleum ether (PE) 11:1), uniform and stable KGM emulsions (d = 7.47 μm, CV = 15.35%) were obtained and crosslinked without emulsion-instable phenomena. View Full-Text
Keywords: uniform small-sized KGM microspheres; premix membrane emulsification; Epoxy-based polymer membrane (EP); alkaline condition uniform small-sized KGM microspheres; premix membrane emulsification; Epoxy-based polymer membrane (EP); alkaline condition
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Mi, Y.; Li, J.; Zhou, W.; Zhang, R.; Ma, G.; Su, Z. Improved Stability of Emulsions in Preparation of Uniform Small-Sized Konjac Glucomanna (KGM) Microspheres with Epoxy-Based Polymer Membrane by Premix Membrane Emulsification. Polymers 2016, 8, 53.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Polymers EISSN 2073-4360 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top