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Polymers 2015, 7(3), 373-389; doi:10.3390/polym7030373

Characterization and Properties of Hydrogels Made from Neutral Soluble Chitosans

1
Viscogel AB, Gunnar Asplunds Allé 32D, Solna SE-171 63, Sweden
2
Department of Biotechnology, Norwegian University of Science and Technology (NTNU), Trondheim N-7491, Norway
*
Author to whom correspondence should be addressed.
Academic Editor: Kjell M. Vårum
Received: 24 November 2014 / Revised: 6 February 2015 / Accepted: 12 February 2015 / Published: 18 February 2015
(This article belongs to the Special Issue Chitin and Chitosans)
View Full-Text   |   Download PDF [1114 KB, uploaded 18 February 2015]   |  

Abstract

The current paper focuses on the preparation and some characteristics of viscoelastic hydrogels, ViscoGels™, made from chitosans having a random acylation pattern. Three different chitosan batches with a high fraction of acetylation were selected based on their Mw, and the impact of degree of cross-linking on these chitosan samples has been studied with respect to the properties of the final hydrogels. Rheological long term (12 month) stability and gelling kinetics data are presented together with results from swelling studies at different pH. Finally, an example illustrating these gels potential as drug delivery vehicles is presented and discussed. View Full-Text
Keywords: chitosan; Viscosan; hydrogel; cross-linked; ViscoGel; visco-elastic; drug delivery; stability; swelling chitosan; Viscosan; hydrogel; cross-linked; ViscoGel; visco-elastic; drug delivery; stability; swelling
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Franzén, H.M.; Draget, K.I.; Langebäck, J.; Nilsen-Nygaard, J. Characterization and Properties of Hydrogels Made from Neutral Soluble Chitosans. Polymers 2015, 7, 373-389.

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