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Polymers 2012, 4(3), 1554-1579; doi:10.3390/polym4031554
Review

Microscale Strategies for Generating Cell-Encapsulating Hydrogels

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Received: 4 May 2012; in revised form: 28 July 2012 / Accepted: 2 August 2012 / Published: 5 September 2012
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Abstract: Hydrogels in which cells are encapsulated are of great potential interest for tissue engineering applications. These gels provide a structure inside which cells can spread and proliferate. Such structures benefit from controlled microarchitectures that can affect the behavior of the enclosed cells. Microfabrication-based techniques are emerging as powerful approaches to generate such cell-encapsulating hydrogel structures. In this paper we introduce common hydrogels and their crosslinking methods and review the latest microscale approaches for generation of cell containing gel particles. We specifically focus on microfluidics-based methods and on techniques such as micromolding and electrospinning.
Keywords: hydrogel; lab-on-a-chip; micromolding; microfluidics; cell encapsulation hydrogel; lab-on-a-chip; micromolding; microfluidics; cell encapsulation
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Selimović, Š.; Oh, J.; Bae, H.; Dokmeci, M.; Khademhosseini, A. Microscale Strategies for Generating Cell-Encapsulating Hydrogels. Polymers 2012, 4, 1554-1579.

AMA Style

Selimović Š, Oh J, Bae H, Dokmeci M, Khademhosseini A. Microscale Strategies for Generating Cell-Encapsulating Hydrogels. Polymers. 2012; 4(3):1554-1579.

Chicago/Turabian Style

Selimović, Šeila; Oh, Jonghyun; Bae, Hojae; Dokmeci, Mehmet; Khademhosseini, Ali. 2012. "Microscale Strategies for Generating Cell-Encapsulating Hydrogels." Polymers 4, no. 3: 1554-1579.


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