Multiple Stimuli-Responsive Hydrogels for Metal-Based Drug Therapy
AbstractA series of homopolymeric and copolymeric hydrogels containing the N-isopropylacrylamide and vinyl monomers with α-amino acid (L-valine and L-phenylalanine) residues have been synthesized and their swelling properties were evaluated under different external stimulations. The hydrogels, obtained with different cross-linking agents (EBA and PEG-DA), have shown unique properties such as biocompatibility in addition to the stimuli-responsive characters. These ‘smart’ hydrogels exhibit single or multiple stimuli-responsiveness which could be used in biomedical applications, including controlled drug delivery. This article focuses on recent developments dealing with the delivery of metal-based drug (cisplatin, lithium) from the stimuli-responsive hydrogels proposed as platforms for cancer and bipolar disorder therapies.
Scifeed alert for new publicationsNever miss any articles matching your research from any publisher
- Get alerts for new papers matching your research
- Find out the new papers from selected authors
- Updated daily for 49'000+ journals and 6000+ publishers
- Define your Scifeed now
Casolaro, M.; Casolaro, I. Multiple Stimuli-Responsive Hydrogels for Metal-Based Drug Therapy. Polymers 2012, 4, 964-985.
Casolaro M, Casolaro I. Multiple Stimuli-Responsive Hydrogels for Metal-Based Drug Therapy. Polymers. 2012; 4(2):964-985.Chicago/Turabian Style
Casolaro, Mario; Casolaro, Ilaria. 2012. "Multiple Stimuli-Responsive Hydrogels for Metal-Based Drug Therapy." Polymers 4, no. 2: 964-985.