Polymers 2012, 4(1), 20-31; doi:10.3390/polym4010020

Hydrodynamic Behavior of Dendrigraft Polylysines in Water and Dimethylformamide

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Received: 2 November 2011; in revised form: 20 December 2011 / Accepted: 23 December 2011 / Published: 2 January 2012
(This article belongs to the Special Issue Dendrimers and Hyperbranched Polymers)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: The four first generations of dendrigraft poly-L-lysine have been studied in dimethylformamide (aprotic solvent) and in 0.2 M NaCl aqueous solutions by isothermal translation diffusion, 1H NMR and viscometry methods. The relationships between diffusion coefficient, intrinsic viscosity and molar mass have been determined for dendrigraft poly-L-lysines, and the scaling index values have been compared to classical trifunctional dendrimers. Dendrimers and dendrigraft poly-L-lysines exhibited similitudes in their hydrodynamic behaviors. Nevertheless, dendrigraft poly-L-lysines displayed a specific behavior in solution. In contrast to dendrimers, a significant change of hydrodynamic dimension of dendrigraft poly-L-lysines according to the nature of the solvent has been observed. In aprotic solvent, the dendrigraft poly-L-lysine dimensions are about two times lower than in aqueous media (i.e., the hydrodynamic volume is contracted by a factor 8 in dimethylformamide), revealing the softness of dendrigraft poly-L-lysine compared to classical trifunctional dendrimers.
Keywords: dendrimer; dendrigraft polylysine; hydrodynamic properties; hydrodynamic radii; diffusion coefficient
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MDPI and ACS Style

Yevlampieva, N.; Dobrodumov, A.; Nazarova, O.; Okatova, O.; Cottet, H. Hydrodynamic Behavior of Dendrigraft Polylysines in Water and Dimethylformamide. Polymers 2012, 4, 20-31.

AMA Style

Yevlampieva N, Dobrodumov A, Nazarova O, Okatova O, Cottet H. Hydrodynamic Behavior of Dendrigraft Polylysines in Water and Dimethylformamide. Polymers. 2012; 4(1):20-31.

Chicago/Turabian Style

Yevlampieva, Natalia; Dobrodumov, Anatolii; Nazarova, Olga; Okatova, Olga; Cottet, Hervé. 2012. "Hydrodynamic Behavior of Dendrigraft Polylysines in Water and Dimethylformamide." Polymers 4, no. 1: 20-31.

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