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Polymers 2011, 3(3), 1076-1090; doi:10.3390/polym3031076

Multimeric, Multifunctional Derivatives of Poly(ethylene glycol)

1
Department of Chemical and Pharmaceutical Sciences, University of Trieste, Piazzale Europa 1, 34127 Trieste, Italy
2
Department of Chemical and Pharmaceutical Sciences, University of Trieste, Via Giorgieri 1, 34127 Trieste, Italy
*
Author to whom correspondence should be addressed.
Received: 13 May 2011 / Revised: 30 June 2011 / Accepted: 12 July 2011 / Published: 13 July 2011
(This article belongs to the Special Issue Water-Soluble Polymers)
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Abstract

This article reviews the use of multifunctional polymers founded on high-molecular weight poly(ethylene glycol) (PEG). The design of new PEG derivatives assembled in a dendrimer-like multimeric fashion or bearing different functionalities on the same molecule is described. Their use as new drug delivery systems based on the conjugation of multiple copies or diversely active drugs on the same biocompatible support is illustrated.
Keywords: poly(ethylene glycol); multifunctional polymers; conjugation; drug delivery poly(ethylene glycol); multifunctional polymers; conjugation; drug delivery
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This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Zacchigna, M.; Cateni, F.; Drioli, S.; Bonora, G.M. Multimeric, Multifunctional Derivatives of Poly(ethylene glycol). Polymers 2011, 3, 1076-1090.

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