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Polymers 2018, 10(2), 144; doi:10.3390/polym10020144

Preparation and Characterization of Porous Core-Shell Fibers for Slow Release of Tea Polyphenols

National Engineering Laboratory for Modern Silk, College of Textile and Engineering, Soochow University, 199 Ren-ai Road, Suzhou 215123, China
Author to whom correspondence should be addressed.
Received: 25 November 2017 / Revised: 17 January 2018 / Accepted: 31 January 2018 / Published: 2 February 2018
(This article belongs to the Special Issue Electrospinning of Nanofibres)
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This study focused on the fabrication, characterization, and release properties of electrospun tea polyphenol (TPP) loaded porous core-shell structured fibers. The morphology, structure and properties of the electrospun TPP loaded porous core-shell fibers were investigated by a combination of Fourier transformation infrared spectroscopy (FTIR), scanning electron microscopy (SEM), contact angle (CA) measurements, transmission electron microscopy (TEM), etc. In addition, the cumulative drug release rate of TPP loaded porous core-shell fibers was determined by ultraviolet (UV) spectrophotometer, and the release mechanism was investigated using Fickian diffusion equation, which would provide the theoretical basis for future study. The results showed TPP loaded porous core-shell structured fibers were successfully prepared by coaxial electrospinning, and the porous structure of the core-shell fibers could further enlarge the specific surface area, enhance the hydrophobic properties, and improve the drug release properties. View Full-Text
Keywords: coaxial electrospinning; porous; core-shell; tea polyphenol; drug release coaxial electrospinning; porous; core-shell; tea polyphenol; drug release

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Wang, Y.; Xu, L. Preparation and Characterization of Porous Core-Shell Fibers for Slow Release of Tea Polyphenols. Polymers 2018, 10, 144.

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