Next Article in Journal
Crystal Chemistry of Zinc Quinaldinate Complexes with Pyridine-Based Ligands
Previous Article in Journal
Effect of Sonication Output Power on the Crystal Structure and Magnetism of SrFe12O19 Nanoparticles
Article Menu
Issue 1 (January) cover image

Export Article

Open AccessReview
Crystals 2018, 8(1), 48; doi:10.3390/cryst8010048

Amorphous Phase Mediated Crystallization: Fundamentals of Biomineralization

Qiushi Academy for Advanced Studies, Zhejiang University, Hangzhou 310027, China
Department of Chemistry and Centre for Biomaterials and Biopathways, Zhejiang University, Hangzhou 310027, China
School of Public Health, Department of Toxicology, Capital Medical University, Beijing 100069, China
Authors to whom correspondence should be addressed.
Received: 18 December 2017 / Revised: 10 January 2018 / Accepted: 11 January 2018 / Published: 19 January 2018
View Full-Text   |   Download PDF [4452 KB, uploaded 19 January 2018]   |  


Many biomineralization systems start from transient amorphous precursor phases, but the exact crystallization pathways and mechanisms remain largely unknown. The study of a well-defined biomimetic crystallization system is key for elucidating the possible mechanisms of biomineralization and monitoring the detailed crystallization pathways. In this review, we focus on amorphous phase mediated crystallization (APMC) pathways and their crystallization mechanisms in bio- and biomimetic-mineralization systems. The fundamental questions of biomineralization as well as the advantages and limitations of biomimetic model systems are discussed. This review could provide a full landscape of APMC systems for biomineralization and inspire new experiments aimed at some unresolved issues for understanding biomineralization. View Full-Text
Keywords: biomineralization; crystallization; amorphous calcium phosphate; amorphous calcium carbonate; nucleation biomineralization; crystallization; amorphous calcium phosphate; amorphous calcium carbonate; nucleation

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Jin, W.; Jiang, S.; Pan, H.; Tang, R. Amorphous Phase Mediated Crystallization: Fundamentals of Biomineralization. Crystals 2018, 8, 48.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics



[Return to top]
Crystals EISSN 2073-4352 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top