Next Article in Journal
Immobilized Palladium Nanoparticles on Zirconium Carboxy-Aminophosphonates Nanosheets as an Efficient Recoverable Heterogeneous Catalyst for Suzuki–Miyaura and Heck Coupling
Next Article in Special Issue
Direct Conversion of Propylene Oxide to 3-Hydroxy Butyric Acid Using a Cobalt Carbonyl Ionic Liquid Catalyst
Previous Article in Journal
Catalytic Acetalization: An Efficient Strategy for High-Value Utilization of Biodiesel-Derived Glycerol
Previous Article in Special Issue
Caprolactam-Based Brønsted Acidic Ionic Liquids for Biodiesel Production from Jatropha Oil
Article Menu
Issue 6 (June) cover image

Export Article

Open AccessCommunication
Catalysts 2017, 7(6), 185; doi:10.3390/catal7060185

Lipase-Catalyzed Synthesis of Indolyl 4H-Chromenes via a Multicomponent Reaction in Ionic Liquid

1
Key Laboratory of Molecular Enzymology and Engineering of Ministry of Education, School of Life Sciences, Jilin University, 2699 Qianjin Street, Changchun 130000, China
2
State Key Laboratory of Supramolecular Structure and Materials, Jilin University, 2699 Qianjin Street, Changchun 130000, China
3
Department of Urology, China-Japan Union Hospital of Jilin University, 126 Xiantai Street, Changchun 130000, China
*
Authors to whom correspondence should be addressed.
Academic Editor: Sandrine Bouquillon
Received: 25 April 2017 / Revised: 28 May 2017 / Accepted: 31 May 2017 / Published: 8 June 2017
(This article belongs to the Special Issue Organocatalysis in Ionic Liquids)
View Full-Text   |   Download PDF [1285 KB, uploaded 12 June 2017]   |  

Abstract

Synthesis of indolyl 4H-chromenes via a three-component reaction catalyzed by lipase in ionic liquidsis reported here for the first time. High yields (77–98%) were obtained when Mucor miehei lipase was used as the catalyst in [EMIM][BF4]. Furthermore, [EMIM][BF4] exhibited good reusability in this enzymatic reaction. This study affords a new example of lipase catalytic promiscuity and broadens the application range of ionic liquid in biocatalysis. View Full-Text
Keywords: lipase; promiscuity; multicomponent; ionic liquid; indolyl-4H-chromene lipase; promiscuity; multicomponent; ionic liquid; indolyl-4H-chromene
Figures

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Zhang, W.; Zhao, Z.; Wang, Z.; Guo, C.; Wang, C.; Zhao, R.; Wang, L. Lipase-Catalyzed Synthesis of Indolyl 4H-Chromenes via a Multicomponent Reaction in Ionic Liquid. Catalysts 2017, 7, 185.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Catalysts EISSN 2073-4344 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top