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Article
Peer-Review Record

Experimental Design to Improve Cell Growth and Ethanol Production in Syngas Fermentation by Clostridium carboxidivorans

Catalysts 2020, 10(1), 59; https://doi.org/10.3390/catal10010059
by Carolina Benevenuti 1, Alanna Botelho 1, Roberta Ribeiro 1, Marcelle Branco 2, Adejanildo Pereira 1, Anna Carolyna Vieira 1, Tatiana Ferreira 2 and Priscilla Amaral 1,*
Reviewer 1: Anonymous
Reviewer 2: Anonymous
Catalysts 2020, 10(1), 59; https://doi.org/10.3390/catal10010059
Submission received: 10 December 2019 / Revised: 19 December 2019 / Accepted: 27 December 2019 / Published: 1 January 2020
(This article belongs to the Special Issue Catalytic Biomass to Renewable Biofuels and Biomaterials)

Round 1

Reviewer 1 Report

Comments:

This manuscript “Experimental design to improve cell growth and ethanol production in syngas fermentation by Clostridium carboxidivorans” aims to obtain a low-cost culture medium, reduced also in number of components, by a sequence of experimental designs in order to improve cell growth and solvents production by Clostridium carboxidivorans using glucose and syngas as carbon sources.

 

Some studies about this subject have already been published.

 

Syngas fermentation by Clostridium carboxidivorans P7 in a horizontal rotating packed bed biofilm reactor with enhanced ethanol production

February 2017Applied Energy 187

DOI: 10.1016/j.apenergy.2016.11.084

Yanwen ShenYanwen ShenRobert C. BrownRobert C. BrownZhiyou Wen

 

 

Fermentation 2017, 3(2), 23; https://doi.org/10.3390/fermentation3020023

Continuous Ethanol Production from Synthesis Gas by Clostridium ragsdalei in a Trickle-Bed Reactor

Mamatha Devarapalli, Randy S. Lewis, and Hasan K. Atiyeh

 

But none of them addresses the theme presented.

This article is clearly written, presents an adequate methodology and the conclusions are supported by the presented results. Moreover, I congratulate the authors for the production/discover of a new medium for syngas fermentation by Clostridium carboxidivorans.

 

So, in my opinion, the article can be published!

Author Response

Please see the attachment.

Author Response File: Author Response.pdf

Reviewer 2 Report

I revised the manuscript “Experimental design to improve cell growth and ethanol production in syngas fermentation by Clostridium carboxidivorans.” submitted to the Catalysts Journal. The paper is interesting. However, I have some concerns, which need to be addressed.

 

There is no chapter in the article titled: Discussion. The discussion is included in the chapter: Results. Move the Discussion from the results chapter to the Discussion chapter.

 

Materials and Methods

Line 334. Which means "e" before 11.05%.

Author Response

 Please see the attachment.

Author Response File: Author Response.pdf

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