Experimental Design to Improve Cell Growth and Ethanol Production in Syngas Fermentation by Clostridium carboxidivorans
Round 1
Reviewer 1 Report
Comments:
This manuscript “Experimental design to improve cell growth and ethanol production in syngas fermentation by Clostridium carboxidivorans” aims to obtain a low-cost culture medium, reduced also in number of components, by a sequence of experimental designs in order to improve cell growth and solvents production by Clostridium carboxidivorans using glucose and syngas as carbon sources.
Some studies about this subject have already been published.
Syngas fermentation by Clostridium carboxidivorans P7 in a horizontal rotating packed bed biofilm reactor with enhanced ethanol production
February 2017Applied Energy 187
DOI: 10.1016/j.apenergy.2016.11.084
Yanwen ShenYanwen ShenRobert C. BrownRobert C. BrownZhiyou Wen
Fermentation 2017, 3(2), 23; https://doi.org/10.3390/fermentation3020023
Continuous Ethanol Production from Synthesis Gas by Clostridium ragsdalei in a Trickle-Bed Reactor
Mamatha Devarapalli, Randy S. Lewis, and Hasan K. Atiyeh
But none of them addresses the theme presented.
This article is clearly written, presents an adequate methodology and the conclusions are supported by the presented results. Moreover, I congratulate the authors for the production/discover of a new medium for syngas fermentation by Clostridium carboxidivorans.
So, in my opinion, the article can be published!
Author Response
Please see the attachment.
Author Response File: Author Response.pdf
Reviewer 2 Report
I revised the manuscript “Experimental design to improve cell growth and ethanol production in syngas fermentation by Clostridium carboxidivorans.” submitted to the Catalysts Journal. The paper is interesting. However, I have some concerns, which need to be addressed.
There is no chapter in the article titled: Discussion. The discussion is included in the chapter: Results. Move the Discussion from the results chapter to the Discussion chapter.
Materials and Methods
Line 334. Which means "e" before 11.05%.
Author Response
Please see the attachment.
Author Response File: Author Response.pdf