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Cancers 2016, 8(1), 13; doi:10.3390/cancers8010013

Cell Proliferation in Neuroblastoma

Department of Surgery, Division of Pediatric Surgery, University of Alabama, Birmingham, AL 35233, USA
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Author to whom correspondence should be addressed.
Academic Editor: Vita Golubovskaya
Received: 20 November 2015 / Revised: 5 January 2016 / Accepted: 8 January 2016 / Published: 12 January 2016
(This article belongs to the Special Issue Cancer Cell Proliferation)
View Full-Text   |   Download PDF [286 KB, uploaded 12 January 2016]

Abstract

Neuroblastoma, the most common extracranial solid tumor of childhood, continues to carry a dismal prognosis for children diagnosed with advanced stage or relapsed disease. This review focuses upon factors responsible for cell proliferation in neuroblastoma including transcription factors, kinases, and regulators of the cell cycle. Novel therapeutic strategies directed toward these targets in neuroblastoma are discussed. View Full-Text
Keywords: neuroblastoma; MYCN; kinases; cell cycle check point inhibitors neuroblastoma; MYCN; kinases; cell cycle check point inhibitors
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Stafman, L.L.; Beierle, E.A. Cell Proliferation in Neuroblastoma. Cancers 2016, 8, 13.

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