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Nutrients 2016, 8(4), 183; doi:10.3390/nu8040183

Potassium and Obesity/Metabolic Syndrome: A Systematic Review and Meta-Analysis of the Epidemiological Evidence

1
Institute of Environmental Medicine, Zhejiang University, Hangzhou 310058, China
2
Ningbo Medical Treatment Center Lihuili Hospital, Ningbo 315000, China
3
Department of Clinic Medicine, Zhejiang University, Hangzhou 310058, China
4
Department of Epidemiology and Biostatistics, Zhejiang University, Hangzhou 310058, China
5
School of Civil Engineering and Geosciences, Newcastle University, Newcastle-upon-Tyne NE1 7RU, UK
6
School of Mathematics and Statistics, University of Glasgow, Glasgow G12 8QW, UK
*
Author to whom correspondence should be addressed.
Received: 25 November 2015 / Revised: 26 February 2016 / Accepted: 17 March 2016 / Published: 25 March 2016
(This article belongs to the Special Issue Potassium and Human Health)
View Full-Text   |   Download PDF [2735 KB, uploaded 25 March 2016]   |  

Abstract

The objective of this study was to investigate the associations between potassium and obesity/metabolic syndrome. We identified eight relevant studies and applied meta-analysis, and nonlinear dose-response analysis to obtain the available evidence. The results of the pooled analysis and systematic review indicated that high potassium intake could not reduce the risk of obesity (pooled OR = 0.78; 95% CI: 0.61–1.01), while serum potassium and urinary sodium-to-potassium ratio was associated with obesity. Potassium intake was associated with metabolic syndrome (pooled OR = 0.75; 95% CI: 0.50–0.97). Nonlinear analysis also demonstrated a protective effect of adequate potassium intake on obesity and metabolic syndrome. Adequate intake of fruits and vegetables, which were the major sources of potassium, was highly recommended. However, additional pertinent studies are needed to examine the underlying mechanism. View Full-Text
Keywords: potassium; obesity; metabolic syndrome; systematic review; meta-analysis potassium; obesity; metabolic syndrome; systematic review; meta-analysis
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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Cai, X.; Li, X.; Fan, W.; Yu, W.; Wang, S.; Li, Z.; Scott, E.M.; Li, X. Potassium and Obesity/Metabolic Syndrome: A Systematic Review and Meta-Analysis of the Epidemiological Evidence. Nutrients 2016, 8, 183.

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