Mechanistic Effects of Calcitriol in Cancer Biology
AbstractBesides its classical biological effects on calcium and phosphorus homeostasis, calcitriol, the active vitamin D metabolite, has a broad variety of actions including anticancer effects that are mediated either transcriptionally and/or via non-genomic pathways. In the context of cancer, calcitriol regulates the cell cycle, induces apoptosis, promotes cell differentiation and acts as anti-inflammatory factor within the tumor microenvironment. In this review, we address the different mechanisms of action involved in the antineoplastic effects of calcitriol. View Full-Text
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Díaz, L.; Díaz-Muñoz, M.; García-Gaytán, A.C.; Méndez, I. Mechanistic Effects of Calcitriol in Cancer Biology. Nutrients 2015, 7, 5020-5050.
Díaz L, Díaz-Muñoz M, García-Gaytán AC, Méndez I. Mechanistic Effects of Calcitriol in Cancer Biology. Nutrients. 2015; 7(6):5020-5050.Chicago/Turabian Style
Díaz, Lorenza; Díaz-Muñoz, Mauricio; García-Gaytán, Ana C.; Méndez, Isabel. 2015. "Mechanistic Effects of Calcitriol in Cancer Biology." Nutrients 7, no. 6: 5020-5050.