Next Article in Journal
Evaluation of Riboflavin Intakes and Status of 20–64-Year-Old Adults in South Korea
Previous Article in Journal
Hormonal and Dietary Characteristics in Obese Human Subjects with and without Food Addiction
Article Menu

Export Article

Open AccessArticle
Nutrients 2015, 7(1), 239-252; doi:10.3390/nu7010239

Fucoidan Supplementation Improves Exercise Performance and Exhibits Anti-Fatigue Action in Mice

1
Graduate Institute of Sports Science, National Taiwan Sport University, Taoyuan 33301, Taiwan
2
Department of Food Science, Fu Jen Catholic University, Taipei 24205, Taiwan
3
Department of Orthopedic Surgery, Taipei Medical University-Shuang Ho Hospital, New Taipei City 23561, Taiwan
4
Department of Neurosurgery, Taipei Medical University-WanFang Hospital, Taipei City 11696, Taiwan
5
Center for General Education, Chang Gung University of Science and Technology, Taoyuan 33301, Taiwan
These authors contributed equally to this work.
*
Authors to whom correspondence should be addressed.
Received: 9 October 2014 / Accepted: 23 December 2014 / Published: 31 December 2014
View Full-Text   |   Download PDF [511 KB, uploaded 31 December 2014]   |  

Abstract

Fucoidan (FCD) is a well-known bioactive constituent of seaweed extract that possess a wide spectrum of activities in biological systems, including anti-cancer, anti-inflammation and modulation of immune systems. However, evidence on the effects of FCD on exercise performance and physical fatigue is limited. Therefore, we investigated the potential beneficial effects of FCD on ergogenic and anti-fatigue functions following physiological challenge. Male ICR mice from three groups (n = 8 per group) were orally administered FCD for 21 days at 0, 310 and 620 mg/kg/day, which were, respectively, designated the vehicle, FCD-1X and FCD-2X groups. The results indicated that the FCD supplementations increased the grip strength (p = 0.0002) and endurance swimming time (p = 0.0195) in a dose-depend manner. FCD treatments also produced dose-dependent decreases in serum levels of lactate (p < 0.0001) and ammonia (p = 0.0025), and also an increase in glucose level (p < 0.0001) after the 15-min swimming test. In addition, FCD supplementation had few subchronic toxic effects. Therefore, we suggest that long-term supplementation with FCD can have a wide spectrum of bioactivities on health promotion, performance improvement and anti-fatigue. View Full-Text
Keywords: brown seaweed extract; exercise performance; forelimb grip strength brown seaweed extract; exercise performance; forelimb grip strength
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Chen, Y.-M.; Tsai, Y.-H.; Tsai, T.-Y.; Chiu, Y.-S.; Wei, L.; Chen, W.-C.; Huang, C.-C. Fucoidan Supplementation Improves Exercise Performance and Exhibits Anti-Fatigue Action in Mice. Nutrients 2015, 7, 239-252.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Nutrients EISSN 2072-6643 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top