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Nutrients 2012, 4(9), 1328-1337; doi:10.3390/nu4091328
Article

Effects of Two Different Levels of Dietary Protein on Body Composition and Protein Nutritional Status of Growing Rats

1
,
2
,
1
 and
3,*
1 Department of Food Science and Experimental Nutrition, Faculty of Pharmaceutical Sciences, University of São Paulo, São Paulo, SP, CEP 05508-000, Brazil 2 School of Arts, Sciences and Humanities, University of São Paulo, São Paulo, SP, CEP 03828-000, Brazil 3 Department of Nutrition, School of Public Health, University of São Paulo, São Paulo, SP, CEP 01246-904, Brazil
* Author to whom correspondence should be addressed.
Received: 9 August 2012 / Revised: 28 August 2012 / Accepted: 11 September 2012 / Published: 20 September 2012
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Abstract

This study aimed to investigate the effect of a high-protein diet on growth, body composition, and protein nutritional status of young rats. Newly-weaned Wistar rats, weighing 45–50 g, were distributed in two experimental groups, according to their diets, which contained 12% (G12) or 26% protein (G26), over a period of 3 weeks. The animals were euthanized at the end of this period and the following analyses were performed: chemical composition of the carcass, proteoglycan synthesis, IGF-I concentration (serum, muscle and cartilage), total tissue RNA, protein concentration (muscle and cartilage) and protein synthesis (muscle and cartilage). The high-protein diet was found to result in a higher fat-free mass and lower fat mass in the carcass, with no difference in growth or protein nutritional status.
Keywords: dietary protein; protein nutritional status; growth; body composition dietary protein; protein nutritional status; growth; body composition
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).
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Tirapegui, J.; Ribeiro, S.M.L.; Pires, I.S.O.; Rogero, M.M. Effects of Two Different Levels of Dietary Protein on Body Composition and Protein Nutritional Status of Growing Rats. Nutrients 2012, 4, 1328-1337.

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