Nutrients 2011, 3(5), 613-636; doi:10.3390/nu3050613
Review

Lactobacillus Adhesion to Mucus

Received: 10 April 2011; in revised form: 5 May 2011 / Accepted: 11 May 2011 / Published: 20 May 2011
(This article belongs to the Special Issue Nutriceuticals)
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Mucus provides protective functions in the gastrointestinal tract and plays an important role in the adhesion of microorganisms to host surfaces. Mucin glycoproteins polymerize, forming a framework to which certain microbial populations can adhere, including probiotic Lactobacillus species. Numerous mechanisms for adhesion to mucus have been discovered in lactobacilli, including partially characterized mucus binding proteins. These mechanisms vary in importance with the in vitro models studied, which could significantly affect the perceived probiotic potential of the organisms. Understanding the nature of mucus-microbe interactions could be the key to elucidating the mechanisms of probiotic adhesion within the host.
Keywords: adhesion; binding; mucin; mucus; MUC2; lactobacillus; MucBP; probiotics
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MDPI and ACS Style

Van Tassell, M.L.; Miller, M.J. Lactobacillus Adhesion to Mucus. Nutrients 2011, 3, 613-636.

AMA Style

Van Tassell ML, Miller MJ. Lactobacillus Adhesion to Mucus. Nutrients. 2011; 3(5):613-636.

Chicago/Turabian Style

Van Tassell, Maxwell L.; Miller, Michael J. 2011. "Lactobacillus Adhesion to Mucus." Nutrients 3, no. 5: 613-636.

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