Sustainability 2012, 4(4), 561-573; doi:10.3390/su4040561
Article

Approaching Resonant Absorption of Environmental Xenobiotics Harmonic Oscillation by Linear Structures

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Received: 1 February 2012; in revised form: 20 March 2012 / Accepted: 21 March 2012 / Published: 30 March 2012
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract: Over the last several decades, it has become increasingly accepted that the term xenobiotic relates to environmental impact, since environmental xenobiotics are understood to be substances foreign to a biological system, which did not exist in nature before their synthesis by humans. In this context, xenobiotics are persistent pollutants such as dioxins and polychlorinated biphenyls, as well as plastics and pesticides. Dangerous and unstable situations can result from the presence of environmental xenobiotics since their harmful effects on humans and ecosystems are often unpredictable. For instance, the immune system is extremely vulnerable and sensitive to modulation by environmental xenobitics. Various experimental assays could be performed to ascertain the immunotoxic potential of environmental xenobiotics, taking into account genetic factors, the route of xenobiotic penetration, and the amount and duration of exposure, as well as the wave shape of the xenobiotic. In this paper, we propose an approach for the analysis of xenobiotic metabolism using mathematical models and corresponding methods. This study focuses on a pattern depicting mathematically modeled processes of resonant absorption of a xenobiotic harmonic oscillation by an organism modulated as an absorbing oscillator structure. We represent the xenobiotic concentration degree through a spatial concentration vector, and we model and simulate the oscillating regime of environmental xenobiotic absorption. It is anticipated that the results could be used to facilitate the assessment of the processes of environmental xenobiotic absorption, distribution, biotransformation and removal within the framework of compartmental analysis, by establishing appropriate mathematical models and simulations.
Keywords: environment; health; environmental xenobiotics; absorption; harmonic oscillation; immunotoxicology
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MDPI and ACS Style

Bulucea, C.A.; Rosen, M.A.; Mastorakis, N.E.; Bulucea, C.A.; Brindusa, C.C. Approaching Resonant Absorption of Environmental Xenobiotics Harmonic Oscillation by Linear Structures. Sustainability 2012, 4, 561-573.

AMA Style

Bulucea CA, Rosen MA, Mastorakis NE, Bulucea CA, Brindusa CC. Approaching Resonant Absorption of Environmental Xenobiotics Harmonic Oscillation by Linear Structures. Sustainability. 2012; 4(4):561-573.

Chicago/Turabian Style

Bulucea, Cornelia A.; Rosen, Marc A.; Mastorakis, Nikos E.; Bulucea, Carmen A.; Brindusa, Corina C. 2012. "Approaching Resonant Absorption of Environmental Xenobiotics Harmonic Oscillation by Linear Structures." Sustainability 4, no. 4: 561-573.

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