Pediatric Reports

651 KiB

Open AccessArticle

Lessons from Prenatal Care Provider-Based Recruitment into the National Children’s Study

by James M. Robbins, Melissa D. Bridges, Elizabeth M. Childers, Roseanne M. Harris and Pearl A. McElfish

Pediatr. Rep. 2015, 7(3), 6056; https://doi.org/10.4081/pr.2015.6056 - 28 Sep 2015

Cited by 3 | Viewed by 374

Abstract

In response to recruitment difficulties experienced by the National Children’s Study, alternatives to the door-to-door recruitment method were pilot tested. This report describes outcomes, successes, and challenges of recruiting women through prenatal care providers in Benton County, Arkansas, USA. Eligible women residing in [...] Read more.

In response to recruitment difficulties experienced by the National Children’s Study, alternatives to the door-to-door recruitment method were pilot tested. This report describes outcomes, successes, and challenges of recruiting women through prenatal care providers in Benton County, Arkansas, USA. Eligible women residing in 14 randomly selected geographic segments were recruited. Data were collected during pregnancy, at birth, and at 3, 6, 9, 12, 18, and 24 months postpartum. Participants were compared to non-enrolled eligible women through birth records. Of 6402 attempts to screen for address eligibility, 468 patients were potentially eligible. Of 221 eligible women approached to participate, 151 (68%) enrolled in the 21-year study. Enrolled women were similar to non-enrolled women in age, marital status, number of prenatal care visits, and gestational age and birth weight of the newborn. Women enrolled from public clinics were more likely to be Hispanic, lower educated, younger and unmarried than those enrolled from private clinics. Sampling geographic areas from historical birth records failed to produce expected equivalent number of births across segments. Enrollment of pregnant women from prenatal care providers was successful. Full article

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Open AccessCase Report

Fecal Impaction Causing Pelvic Venous Compression and Edema

by Sara Naramore, Faisal Aziz, Chandran Paul Alexander, Sosamma Methratta, Robert Cilley and Dorothy Rocourt

Pediatr. Rep. 2015, 7(3), 5999; https://doi.org/10.4081/pr.2015.5999 - 28 Sep 2015

Cited by 5 | Viewed by 544

Abstract

Chronic constipation is a common condition which may result in fecal impaction. A 13-year-old male with chronic constipation and encopresis presented with fecal impaction for three weeks. The impaction caused abdominal pain, distension, encopresis, and decreased oral intake. He was found in severe [...] Read more.

Chronic constipation is a common condition which may result in fecal impaction. A 13-year-old male with chronic constipation and encopresis presented with fecal impaction for three weeks. The impaction caused abdominal pain, distension, encopresis, and decreased oral intake. He was found in severe distress with non-pitting edema of his feet and ankles along with perineal edema. The pedal edema worsened after receiving a fluid bolus, so concern arose for venous compression or a thrombus. A Duplex Ultrasound demonstrated changes in the venous waveforms of the bilateral external iliac and common femoral veins without thrombosis. Manual disimpaction and polyethylene glycol 3350 with electrolytes resolved the pedal and perineal edema. Four months later, he had soft bowel movements without recurrence of the edema. A repeat Duplex Ultrasound was normal. We present a child in whom severe fecal impaction caused pelvic venous compression resulting in bilateral pedal and perineal edema. Full article

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Open AccessCase Report

Recurrent Rhino-Ocular-Cerebral Mucormycosis in a Leukemic Child: A Case Report and Review of Pediatric Literature

by Francesco De Leonardis, Teresa Perillo, Giuseppe Giudice, Gianfranco Favia and Nicola Santoro

Pediatr. Rep. 2015, 7(3), 5938; https://doi.org/10.4081/pr.2015.5938 - 28 Sep 2015

Cited by 9 | Viewed by 361

Abstract

Mucormycosis is an uncommon but severe fungal infection, typically observed in immunocompromized patients. We report a case of acute lymphoblastic leukemia complicated by rhino-oculo-cerebral mucormycosis in a pediatric patient. Combination lipid polyeneechinocandin therapy, along with surgical debridement appeared to be effective. Nevertheless, a [...] Read more.

Mucormycosis is an uncommon but severe fungal infection, typically observed in immunocompromized patients. We report a case of acute lymphoblastic leukemia complicated by rhino-oculo-cerebral mucormycosis in a pediatric patient. Combination lipid polyeneechinocandin therapy, along with surgical debridement appeared to be effective. Nevertheless, a severe relapse occurred during posaconazole prophylaxis; antifungal therapy, hemimaxillectomy and suspension of chemotherapy were performed. Although mucormycosis is a frequently lethal infection, prompt diagnosis and aggressive treatment can be successful even in cases of relapse. Full article

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Open AccessCase Report

Adrenal Hypoplasia Congenita: A Rare Cause of Primary Adrenal Insufficiency and Hypogonadotropic Hypogonadism

by Marta Loureiro, Filipa Reis, Brígida Robalo, Carla Pereira and Lurdes Sampaio

Pediatr. Rep. 2015, 7(3), 5936; https://doi.org/10.4081/pr.2015.5936 - 28 Sep 2015

Cited by 5 | Viewed by 469

Abstract

Primary adrenal insufficiency is defined by the impaired synthesis of adrenocortical hormones due to an intrinsic disease of the adrenal cortex. Determining its etiology is crucial to allow adequate long-term management and genetic counseling. We report the case of a male adolescent that [...] Read more.

Primary adrenal insufficiency is defined by the impaired synthesis of adrenocortical hormones due to an intrinsic disease of the adrenal cortex. Determining its etiology is crucial to allow adequate long-term management and genetic counseling. We report the case of a male adolescent that presented in the neonatal period with adrenal crisis and received replacement therapy for primary adrenal insufficiency. During follow-up, adrenal hypoplasia congenita (AHC) was suspected given his persistently raised adrenocorticotropic hormone levels, with markedly low 17-OH progesterone and androstenedione levels. DNA sequence analysis revealed a mutation in NR0B1 gene (c.1292delG), confirming the diagnosis. Delayed puberty and persistent low levels of gonadotropins led to testosterone replacement therapy. X-linked AHC is a rare cause of primary adrenal insufficiency and hypogonadotropic hypogonadism, related to mutations in NR0B1 gene. Despite its rarity, AHC should be considered in patients who present with primary adrenal failure, low levels of 17-OH progesterone and hypogonadotropic hypogonadism. Full article

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Open AccessCase Report

Rare but Lethal Disease of Childhood: Metastatic, Muscle Invasive Bladder Cancer

by Serdar Aykan, Emrah Yuruk, Murat Tuken, Mustafa Zafer Temiz and Sule Ozsoy

Pediatr. Rep. 2015, 7(3), 5928; https://doi.org/10.4081/pr.2015.5928 - 28 Sep 2015

Cited by 7 | Viewed by 385

Abstract

Bladder cancer is the most common malignancy of urinary tract and the seventh most common cancer in men with the peak incidence in the sixth decade of life. Our knowledge about bladder tumors in pediatric age group mainly relies on case series. The [...] Read more.

Bladder cancer is the most common malignancy of urinary tract and the seventh most common cancer in men with the peak incidence in the sixth decade of life. Our knowledge about bladder tumors in pediatric age group mainly relies on case series. The reported cases are mostly low grade and non-muscle invasive. We herein present a case of a 17- year-old male with metastatic high-grade muscle-invasive bladder cancer who was presented with macroscopic hematuria and flank pain. Full article

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Open AccessCase Report

A Rare Case of Painful Goiter Secondary to Pediatric Hashimoto’s Thyroiditis Requiring Thyroidectomy for Pain Control

by Liladhar Kashyap, Abdulhameed Alsaheel, Rohan Walvekar, Lawrence Simon and Ricardo Gomez

Pediatr. Rep. 2015, 7(3), 5914; https://doi.org/10.4081/pr.2015.5914 - 28 Sep 2015

Cited by 4 | Viewed by 498

Abstract

Hashimoto’s thyroiditis (HT) usually presents as painless thyroid swelling. Painful pediatric HT is a rare condition with limited literature on pain management. We report a 15- year-old female who presented with 4 weeks history of fatigue, malaise and progressive, painful midline thyroid swelling. [...] Read more.

Hashimoto’s thyroiditis (HT) usually presents as painless thyroid swelling. Painful pediatric HT is a rare condition with limited literature on pain management. We report a 15- year-old female who presented with 4 weeks history of fatigue, malaise and progressive, painful midline thyroid swelling. There was no difficulty in swallowing, no fever or recent upper respiratory infection symptoms. Exam was remarkable for diffusely enlarged, very tender, and non-nodular thyroid. Thyroid function tests, C-reactive protein, and complete blood count were normal. Ultrasound revealed diffusely enlarged non-nodular, non-cystic gland with mild increased vascularity. Diagnosis of HT was confirmed by biopsy and thyroid antibodies. Over a 6 week period, pain management with ibuprofen, levothyroxine, corticosteroid, gabapentin and amitriptyline was unsuccessful. Ultimately, total thyroidectomy resulted in complete resolution of thyroid pain. We can conclude that thyroidectomy may be considered for the rare case of painful HT in children. Full article

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Open AccessCase Report

Acute Myositis Associated with Concurrent Infection of Rotavirus and Norovirus in a 2-Year-Old Girl

by Kei Yamamoto, Seiji Fukuda, Yuichi Mushimoto, Noriaki Minami, Rie Kanai, Kazuki Tsukamoto and Seiji Yamaguchi

Pediatr. Rep. 2015, 7(3), 5873; https://doi.org/10.4081/pr.2015.5873 - 28 Sep 2015

Cited by 5 | Viewed by 497

Abstract

Rotavirus and norovirus are common pathogens associated with gastroenteritis in children. Although rotavirus occasionally induces central nervous system disease, only 3 cases with rotavirus-induced acute myositis have been reported in the English literature. We recently treated a female patient with acute myositis associated [...] Read more.

Rotavirus and norovirus are common pathogens associated with gastroenteritis in children. Although rotavirus occasionally induces central nervous system disease, only 3 cases with rotavirus-induced acute myositis have been reported in the English literature. We recently treated a female patient with acute myositis associated with gastroenteritis induced by concurrent infection with rotavirus and norovirus. Having suffered from gastroenteritis for 3 days, she suddenly developed myositis affecting her lower extremities with concomitant creatine kinase elevation. Herein, we present our patient and review the previous cases including those reported in the Japanese literature. Full article

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Pediatr. Rep., Volume 7, Issue 3 (September 2015) – 7 articles

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