Chloroviruses Have a Sweet Tooth
AbstractChloroviruses are large double-stranded DNA (dsDNA) viruses that infect certain isolates of chlorella-like green algae. They contain up to approximately 400 protein-encoding genes and 16 transfer RNA (tRNA) genes. This review summarizes the unexpected finding that many of the chlorovirus genes encode proteins involved in manipulating carbohydrates. These include enzymes involved in making extracellular polysaccharides, such as hyaluronan and chitin, enzymes that make nucleotide sugars, such as GDP-L-fucose and GDP-D-rhamnose and enzymes involved in the synthesis of glycans attached to the virus major capsid proteins. This latter process differs from that of all other glycoprotein containing viruses that traditionally use the host endoplasmic reticulum and Golgi machinery to synthesize and transfer the glycans. View Full-Text
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Van Etten, J.L.; Agarkova, I.; Dunigan, D.D.; Tonetti, M.; De Castro, C.; Duncan, G.A. Chloroviruses Have a Sweet Tooth. Viruses 2017, 9, 88.
Van Etten JL, Agarkova I, Dunigan DD, Tonetti M, De Castro C, Duncan GA. Chloroviruses Have a Sweet Tooth. Viruses. 2017; 9(4):88.Chicago/Turabian Style
Van Etten, James L.; Agarkova, Irina; Dunigan, David D.; Tonetti, Michela; De Castro, Christina; Duncan, Garry A. 2017. "Chloroviruses Have a Sweet Tooth." Viruses 9, no. 4: 88.
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