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Viruses 2013, 5(9), 2253-2259; doi:10.3390/v5092253

Seroprevalence of Human Herpesvirus-8 in HIV-1 Infected and Uninfected Individuals in Cameroon

1,2,* , 1, 1, 1, 3 and 1,*
1 Laboratory of Molecular Virology, Division of Emerging and Transmission Transmitted Diseases, Office of Blood Review and Research , Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA 2 Chantal Biya International Reference Centre, Yaoundé, P.O Box 3077, Cameroon 3 Laboratoire d'Analyses Médicales de Nkoldongo, Yaoundé P.O Box 20025, Cameroon
* Authors to whom correspondence should be addressed.
Received: 5 July 2013 / Revised: 8 August 2013 / Accepted: 13 September 2013 / Published: 19 September 2013
(This article belongs to the Section Animal Viruses)
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We evaluated the prevalence of HHV-8 antibodies in 516 plasma samples collected from HIV positive and negative patients from blood banks and urban areas of Cameroon. Among HIV-1 positive samples, HHV-8 seropositivity rate was 61% based on combined reactivity using both ELISA and IFA techniques. HIV negative samples showed 62% seropositivity rate for HHV-8 antibodies. Our results indicate a high HHV-8 prevalence rate in both HIV infected and uninfected individuals in Cameroon.
Keywords: HHV-8; HIV-1; serology; prevalence; Cameroon HHV-8; HIV-1; serology; prevalence; Cameroon
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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Mbondji-Wonje, C.; Ragupathy, V.; Lee, S.; Wood, O.; Awazi, B.; Hewlett, I.K. Seroprevalence of Human Herpesvirus-8 in HIV-1 Infected and Uninfected Individuals in Cameroon. Viruses 2013, 5, 2253-2259.

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