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Viruses 2013, 5(9), 2253-2259; doi:10.3390/v5092253

Seroprevalence of Human Herpesvirus-8 in HIV-1 Infected and Uninfected Individuals in Cameroon

1,2,* , 1, 1, 1, 3 and 1,*
1 Laboratory of Molecular Virology, Division of Emerging and Transmission Transmitted Diseases, Office of Blood Review and Research , Center for Biologics Evaluation and Research, Food and Drug Administration, 1401 Rockville Pike, Rockville, MD 20852, USA 2 Chantal Biya International Reference Centre, Yaoundé, P.O Box 3077, Cameroon 3 Laboratoire d'Analyses Médicales de Nkoldongo, Yaoundé P.O Box 20025, Cameroon
* Authors to whom correspondence should be addressed.
Received: 5 July 2013 / Revised: 8 August 2013 / Accepted: 13 September 2013 / Published: 19 September 2013
(This article belongs to the Section Animal Viruses)
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We evaluated the prevalence of HHV-8 antibodies in 516 plasma samples collected from HIV positive and negative patients from blood banks and urban areas of Cameroon. Among HIV-1 positive samples, HHV-8 seropositivity rate was 61% based on combined reactivity using both ELISA and IFA techniques. HIV negative samples showed 62% seropositivity rate for HHV-8 antibodies. Our results indicate a high HHV-8 prevalence rate in both HIV infected and uninfected individuals in Cameroon.
Keywords: HHV-8; HIV-1; serology; prevalence; Cameroon HHV-8; HIV-1; serology; prevalence; Cameroon
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Mbondji-Wonje, C.; Ragupathy, V.; Lee, S.; Wood, O.; Awazi, B.; Hewlett, I.K. Seroprevalence of Human Herpesvirus-8 in HIV-1 Infected and Uninfected Individuals in Cameroon. Viruses 2013, 5, 2253-2259.

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