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Modulation of Apoptotic Pathways by Human Papillomaviruses (HPV): Mechanisms and Implications for Therapy
Viruses 2012, 4(12), 3851-3858; doi:10.3390/v4123851
Review

The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature

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Received: 22 November 2012; in revised form: 14 December 2012 / Accepted: 17 December 2012 / Published: 18 December 2012
(This article belongs to the Section Animal Viruses)
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Abstract: Human Papillomavirus (HPV) infection is the most common sexually transmitted infection (STI) worldwide. Incidence rates of HPV infection among human immunodeficiency virus (HIV)-infected individuals are well documented and are several-fold higher than among HIV-uninfected individuals. Few studies have demonstrated an increased risk for acquiring HIV infection in those with HPV infection, and this risk seems to be higher when HPV strains are of high-risk oncogenic potential. The estimated prevalence of high-risk oncogenic HPV infection is highest in men who have sex with men (MSM), a particularly vulnerable group with high prevalence rates of HIV infection and other STIs. In this paper, we provide a comprehensive review of the available literature on the role of HPV infection in HIV acquisition. Our review includes data from cross-sectional and longitudinal studies.
Keywords: human papillomavirus; human immunodeficiency virus; men who have sex with men; HIV incidence; review; HPV testing human papillomavirus; human immunodeficiency virus; men who have sex with men; HIV incidence; review; HPV testing
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Brown, B.; Davtyan, M.; Galea, J.; Chow, E.; Leon, S.; Klausner, J.D. The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature. Viruses 2012, 4, 3851-3858.

AMA Style

Brown B, Davtyan M, Galea J, Chow E, Leon S, Klausner JD. The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature. Viruses. 2012; 4(12):3851-3858.

Chicago/Turabian Style

Brown, Brandon; Davtyan, Mariam; Galea, Jerome; Chow, Erica; Leon, Segundo; Klausner, Jeffrey D. 2012. "The Role of Human Papillomavirus in Human Immunodeficiency Virus Acquisition in Men who Have Sex with Men: A Review of the Literature." Viruses 4, no. 12: 3851-3858.


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