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Viruses 2010, 2(11), 2436-2442; doi:10.3390/v2112436

Making of Viral Replication Organelles by Remodeling Interior Membranes

Department of Plant Pathology, University of Kentucky, 201F Plant Science Building, Lexington, KY 40546, USA
Author to whom correspondence should be addressed.
Received: 8 October 2010 / Revised: 29 October 2010 / Accepted: 1 November 2010 / Published: 5 November 2010
(This article belongs to the Section Editorial)
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Positive-stranded RNA (+RNA) viruses exploit host cell machinery by subverting host proteins and membranes and altering cellular pathways during infection. To achieve robust replication, some +RNA viruses, such as poliovirus (PV), build special intracellular compartments, called viral replication organelles. A recent work from the Altan-Bonnett laboratory [1] gave new insights into the formation of poliovirus replication organelles, which are unique subcellular structures containing many individual replication complexes as a result of dynamic cellular membrane remodeling.
Keywords: virus replication; membrane remodeling; host factor; poliovirus; Arf1 virus replication; membrane remodeling; host factor; poliovirus; Arf1
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

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MDPI and ACS Style

Sasvari, Z.; Nagy, P.D. Making of Viral Replication Organelles by Remodeling Interior Membranes. Viruses 2010, 2, 2436-2442.

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