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Viruses 2018, 10(3), 122; https://doi.org/10.3390/v10030122

Together Forever: Bacterial–Viral Interactions in Infection and Immunity

Center for Inflammation, Immunity and Infection, Institute for Biomedical Sciences, Georgia State University, Atlanta, GA 30303, USA
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Received: 16 February 2018 / Revised: 28 February 2018 / Accepted: 6 March 2018 / Published: 10 March 2018
(This article belongs to the Section Bacterial Viruses)
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Abstract

Most viruses first encounter host cells at mucosal surfaces, which are typically colonized by a complex ecosystem of microbes collectively referred to as the microbiota. Recent studies demonstrate the microbiota plays an important role in mediating host–viral interactions and determining the outcomes of these encounters. This review outlines recently described examples of how bacteria and viruses impact each other particularly during infectious processes. Mechanistically, these effects can be broadly categorized as reflecting direct bacterial–viral interactions and/or involving microbial impacts upon innate and/or adaptive immunity. View Full-Text
Keywords: rotavirus; reovirus; LPS; inflammation rotavirus; reovirus; LPS; inflammation
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This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).
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Shi, Z.; Gewirtz, A.T. Together Forever: Bacterial–Viral Interactions in Infection and Immunity. Viruses 2018, 10, 122.

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