A Review of PMMA Bone Cement and Intra‐Cardiac Embolism
AbstractPercutaneous vertebroplasty procedure is of major importance, given the significantly increasing aging population and the higher number of orthopedic procedures related to vertebral compression fractures. Vertebroplasty is a complex technique involving the injection of polymethylmethacrylate (PMMA) into the compressed vertebral body for mechanical stabilization of the fracture. Our understanding and ability to modify these mechanisms through alterations in cement material is rapidly evolving. However, the rate of cardiac complications secondary to PMMA injection and subsequent cement leakage has increased with time. The following review considers the main effects of PMMA bone cement on the heart, and the extent of influence of the materials on cardiac embolism. Clinically, cement leakage results in life‐threatening cardiac injury. The convolution of this outcome through an appropriate balance of complex material properties is highlighted via clinical case reports. View Full-Text
Share & Cite This Article
Shridhar, P.; Chen, Y.; Khalil, R.; Plakseychuk, A.; Cho, S.K.; Tillman, B.; Kumta, P.N.; Chun, Y. A Review of PMMA Bone Cement and Intra‐Cardiac Embolism. Materials 2016, 9, 821.
Shridhar P, Chen Y, Khalil R, Plakseychuk A, Cho SK, Tillman B, Kumta PN, Chun Y. A Review of PMMA Bone Cement and Intra‐Cardiac Embolism. Materials. 2016; 9(10):821.Chicago/Turabian Style
Shridhar, Puneeth; Chen, Yanfei; Khalil, Ramzi; Plakseychuk, Anton; Cho, Sung K.; Tillman, Bryan; Kumta, Prashant N.; Chun, YoungJae. 2016. "A Review of PMMA Bone Cement and Intra‐Cardiac Embolism." Materials 9, no. 10: 821.
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.