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Materials 2015, 8(11), 7563-7577; doi:10.3390/ma8115397

Intelligent Optimization of the Film-to-Fiber Ratio of a Degradable Braided Bicomponent Ureteral Stent

1
Engineering Research Center of Digitized Textile & Apparel Technology, Ministry of Education, College of Information Science and Technology, Donghua University, Shanghai 201620, China
2
Key Laboratory of Textile Science and Technology, Ministry of Education, College of Textiles, Donghua University, Shanghai 201620, China
*
Author to whom correspondence should be addressed.
Academic Editor: Juergen Stampfl
Received: 21 July 2015 / Revised: 5 September 2015 / Accepted: 26 October 2015 / Published: 11 November 2015
(This article belongs to the Section Biomaterials)
View Full-Text   |   Download PDF [2903 KB, uploaded 11 November 2015]   |  

Abstract

A hierarchical support vector regression (SVR) model (HSVRM) was employed to correlate the compositions and mechanical properties of bicomponent stents composed of poly(lactic-co-glycolic acid) (PGLA) film and poly(glycolic acid) (PGA) fibers for urethral repair for the first time. PGLA film and PGA fibers could provide ureteral stents with good compressive and tensile properties, respectively. In bicomponent stents, high film content led to high stiffness, while high fiber content resulted in poor compressional properties. To simplify the procedures to optimize the ratio of PGLA film and PGA fiber in the stents, a hierarchical support vector regression model (HSVRM) and particle swarm optimization (PSO) algorithm were used to construct relationships between the film-to-fiber weight ratio and the measured compressional/tensile properties of the stents. The experimental data and simulated data fit well, proving that the HSVRM could closely reflect the relationship between the component ratio and performance properties of the ureteral stents. View Full-Text
Keywords: bicomponent; ureteral stent; biodegradable; HSVRM model; PSO algorithm bicomponent; ureteral stent; biodegradable; HSVRM model; PSO algorithm
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

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MDPI and ACS Style

Liu, X.; Li, F.; Ding, Y.; Zou, T.; Wang, L.; Hao, K. Intelligent Optimization of the Film-to-Fiber Ratio of a Degradable Braided Bicomponent Ureteral Stent. Materials 2015, 8, 7563-7577.

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