Mechanisms of in Vivo Degradation and Resorption of Calcium Phosphate Based Biomaterials
Abstract
:1. Introduction
Compound Name | Chemical Formula | Symbol | Mineral | Ca/P Ionic Ratio | Density (g/cm3) | Solubility at 25 °C (mg/L) |
---|---|---|---|---|---|---|
Monocalcium phosphate monohydrate | Ca(H2PO4)2·H2O | MCPM | - | 0.5 | 2.23 | ~18,000 |
Monocalcium phosphate anhydrous | Ca(H2PO4)2 | MCPA | - | 0.5 | 2.58 | ~17,000 |
Dicalcium phosphate dehydrate | CaHPO4·2H2O | DCPD | Brushite | 1.0 | 2.27 | ~88 |
Dicalcium phosphate anhydrous | CaHPO4 | DCPA | Monetite | 1.0 | 2.92 | ~48 |
Octacalcium phosphate | Ca8(HPO4)2(PO4)4·5H2O | OCP | - | 1.33 | 2.61 | ~8.1 |
α-Tricalcium phosphate | α-Ca3(PO4)2 | α-TCP | - | 1.5 | 2.86 | ~2.5 |
β-Tricalcium phosphate | β-Ca3(PO4)2 | Β-TCP | - | 1.5 | 3.07 | ~0.5 |
Amorphous calcium phosphate | Ca3(PO4)2·nH2O n = 3–4.5; 15%–20% H,O | ACP | - | 1.5 | 3.01 | 25.6–32.8 |
Precipitated hydroxyapatite | Ca10−x(HPO4)x(PO4)6−x(OH)2−x | PHA | - | 1.33–1.67 | 3.16 | Not available |
Calcium-deficient hydroxyapatite | Ca10−x(HPO4)x(PO4)6−x(OH)2−x (0 < x < 1) | CDHA | - | 1.5–1.67 | 3.16 | ~9.4 |
Hydroxyapatite | Ca10(PO4)6(OH)2 | HA | Hydroxyapatite | 1.67 | 3.16 | ~0.3 |
Oxyapatite | Ca10(PO4)6O | OXA | - | 1.67 | 3.20 | Not available |
Fluorapatite | Ca10(PO4)6F2 | FA | - | 1.67 | 3.18 | ~0.2 |
Tetracalcium phosphate | Ca2(PO4)2O | TTCP | Hilgenstockite | 2.0 | 3.05 | ~0.7 |
2. In Vivo Degradation and Resorption of Calcium Phosphates
3. Conclusions
Acknowledgments
Author Contributions
Conflicts of Interest
References
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Sheikh, Z.; Abdallah, M.-N.; Hanafi, A.A.; Misbahuddin, S.; Rashid, H.; Glogauer, M. Mechanisms of in Vivo Degradation and Resorption of Calcium Phosphate Based Biomaterials. Materials 2015, 8, 7913-7925. https://doi.org/10.3390/ma8115430
Sheikh Z, Abdallah M-N, Hanafi AA, Misbahuddin S, Rashid H, Glogauer M. Mechanisms of in Vivo Degradation and Resorption of Calcium Phosphate Based Biomaterials. Materials. 2015; 8(11):7913-7925. https://doi.org/10.3390/ma8115430
Chicago/Turabian StyleSheikh, Zeeshan, Mohamed-Nur Abdallah, Ahmed Abdalla Hanafi, Syed Misbahuddin, Haroon Rashid, and Michael Glogauer. 2015. "Mechanisms of in Vivo Degradation and Resorption of Calcium Phosphate Based Biomaterials" Materials 8, no. 11: 7913-7925. https://doi.org/10.3390/ma8115430