Materials 2013, 6(4), 1391-1402; doi:10.3390/ma6041391
Article

Chitosonic® Acid as a Novel Cosmetic Ingredient: Evaluation of its Antimicrobial, Antioxidant and Hydration Activities

1 Department of Cosmetic Science and Management, Mackay Medicine, Nursing and Management College, 92 Shengjing Road, Beitou, Taipei 11260, Taiwan 2 Advanced Delivery Technology Co. Ltd, 5F, D Building, No.120, Zhonghua Rd., Hsinchu Industrial Park, Hukou Township, Hsinchu 30352, Taiwan 3 Department of Cosmetic Science, Providence University, No. 200, Sec. 7, Taiwan Boulevard, Shalu, Taichung 43301, Taiwan
* Authors to whom correspondence should be addressed.
Received: 30 November 2012; in revised form: 22 February 2013 / Accepted: 20 March 2013 / Published: 28 March 2013
(This article belongs to the Special Issue Advances in Cosmetics)
PDF Full-text Download PDF Full-Text [297 KB, uploaded 28 March 2013 14:36 CET]
Abstract: Chitosonic® Acid, carboxymethyl hexanoyl chitosan, is a novel chitosan material that has recently been accepted by the Personal Care Products Council as a new cosmetic ingredient with the INCI (International Nomenclature of Cosmetic Ingredients) name Carboxymethyl Caprooyl Chitosan. In this study, we analyze several important cosmetic characteristics of Chitosonic® Acid. Our results demonstrate that Chitosonic® Acid is a water-soluble chitosan derivative with a high HLB value. Chitosonic® Acid can form a nano-network structure when its concentration is higher than 0.5% and can self-assemble into a nanosphere structure when its concentration is lower than 0.2%. Chitosonic® Acid has potent antimicrobial activities against gram-positive bacteria, gram-negative bacteria and fungus. Chitosonic® Acid also has moderate DPPH radical scavenging activity. Additionally, Chitosonic® Acid exhibits good hydration activity for absorbing and retaining water molecules with its hydrophilic groups. From a safety point of view, Chitosonic® Acid has no cytotoxicity to L-929 cells if its concentration is less than 0.5%. Moreover, Chitosonic® Acid has good compatibilities with various normal cosmetic ingredients. Therefore, we propose that Chitosonic® Acid has the potential to be a widely used ingredient in various types of cosmetic products.
Keywords: antimicrobial activity; antioxidant activity; Carboxymethyl Caprooyl Chitosan; Chitosonic® Acid; cosmetic ingredient; hydration activity

Article Statistics

Load and display the download statistics.

Citations to this Article

Cite This Article

MDPI and ACS Style

Lee, S.-M.; Liu, K.-H.; Liu, Y.-Y.; Chang, Y.-P.; Lin, C.-C.; Chen, Y.-S. Chitosonic® Acid as a Novel Cosmetic Ingredient: Evaluation of its Antimicrobial, Antioxidant and Hydration Activities. Materials 2013, 6, 1391-1402.

AMA Style

Lee S-M, Liu K-H, Liu Y-Y, Chang Y-P, Lin C-C, Chen Y-S. Chitosonic® Acid as a Novel Cosmetic Ingredient: Evaluation of its Antimicrobial, Antioxidant and Hydration Activities. Materials. 2013; 6(4):1391-1402.

Chicago/Turabian Style

Lee, Shu-Mei; Liu, Kun-Ho; Liu, Yen-Yu; Chang, Yen-Po; Lin, Chih-Chien; Chen, Yi-Shyan. 2013. "Chitosonic® Acid as a Novel Cosmetic Ingredient: Evaluation of its Antimicrobial, Antioxidant and Hydration Activities." Materials 6, no. 4: 1391-1402.

Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert