Next Article in Journal
Lithium Ion Battery Anode Aging Mechanisms
Previous Article in Journal
Fabrication of Cellulose Film with Enhanced Mechanical Properties in Ionic Liquid 1-Allyl-3-methylimidaxolium Chloride (AmimCl)
Previous Article in Special Issue
Thermo-Mechanical Behavior of Textile Heating Fabric Based on Silver Coated Polymeric Yarn
Article Menu

Export Article

Open AccessReview
Materials 2013, 6(4), 1285-1309; doi:10.3390/ma6041285

Alginate-Based Biomaterials for Regenerative Medicine Applications

School of Materials Science and Engineering, Nanjing University of Science and Technology, Nanjing 210094, China
*
Author to whom correspondence should be addressed.
Received: 31 December 2012 / Revised: 19 February 2013 / Accepted: 19 March 2013 / Published: 26 March 2013
(This article belongs to the Special Issue Advances in Multifunctional Materials)
View Full-Text   |   Download PDF [329 KB, uploaded 26 March 2013]   |  

Abstract

Alginate is a natural polysaccharide exhibiting excellent biocompatibility and biodegradability, having many different applications in the field of biomedicine. Alginate is readily processable for applicable three-dimensional scaffolding materials such as hydrogels, microspheres, microcapsules, sponges, foams and fibers. Alginate-based biomaterials can be utilized as drug delivery systems and cell carriers for tissue engineering. Alginate can be easily modified via chemical and physical reactions to obtain derivatives having various structures, properties, functions and applications. Tuning the structure and properties such as biodegradability, mechanical strength, gelation property and cell affinity can be achieved through combination with other biomaterials, immobilization of specific ligands such as peptide and sugar molecules, and physical or chemical crosslinking. This review focuses on recent advances in the use of alginate and its derivatives in the field of biomedical applications, including wound healing, cartilage repair, bone regeneration and drug delivery, which have potential in tissue regeneration applications. View Full-Text
Keywords: biomaterials; alginate; regenerative medicine; tissue engineering; drug delivery biomaterials; alginate; regenerative medicine; tissue engineering; drug delivery
This is an open access article distributed under the Creative Commons Attribution License (CC BY 3.0).

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Sun, J.; Tan, H. Alginate-Based Biomaterials for Regenerative Medicine Applications. Materials 2013, 6, 1285-1309.

Show more citation formats Show less citations formats

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top