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Materials 2011, 4(1), 84-102; doi:10.3390/ma4010084

Optical and Electric Multifunctional CMOS Image Sensors for On-Chip Biosensing Applications

1,2,* , 1
1 Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Nara 630-0101, Japan 2 PRESTO, Japan Science and Technology Agency, 3–5 Sanba, Chiyoda, Tokyo, 102-0075, Japan
* Author to whom correspondence should be addressed.
Received: 10 December 2010 / Accepted: 27 December 2010 / Published: 29 December 2010
(This article belongs to the Special Issue Bio-devices and Materials)
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In this review, the concept, design, performance, and a functional demonstration of multifunctional complementary metal-oxide-semiconductor (CMOS) image sensors dedicated to on-chip biosensing applications are described. We developed a sensor architecture that allows flexible configuration of a sensing pixel array consisting of optical and electric sensing pixels, and designed multifunctional CMOS image sensors that can sense light intensity and electric potential or apply a voltage to an on-chip measurement target. We describe the sensors’ architecture on the basis of the type of electric measurement or imaging functionalities.
Keywords: CMOS image sensor; on-chip imaging; electric imaging CMOS image sensor; on-chip imaging; electric imaging
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Tokuda, T.; Noda, T.; Sasagawa, K.; Ohta, J. Optical and Electric Multifunctional CMOS Image Sensors for On-Chip Biosensing Applications. Materials 2011, 4, 84-102.

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