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Materials 2010, 3(9), 4657-4667; doi:10.3390/ma3094657
Article

Growth and Structure of ZnO Nanorods on a Sub-Micrometer Glass Pipette and Their Application as Intracellular Potentiometric Selective Ion Sensors

1,* , 1
, 1
, 2
, 2
, 2
, 2
, 3
 and 3
1 Department of Science and Technology, Campus Norrköping, Linköping University, SE-60174 Norrköping Sweden 2 Department of Clinical and Experimental Medicine, Division of Cell Biology, Linköping University, SE-58185 Linköping, Sweden 3 Department of Physics (IFM), Linkoping University, SE-581 83 Linköping, Sweden
* Author to whom correspondence should be addressed.
Received: 20 July 2010 / Revised: 2 September 2010 / Accepted: 7 September 2010 / Published: 9 September 2010
(This article belongs to the Special Issue Bio-devices and Materials)
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Abstract

This paper presents the growth and structure of ZnO nanorods on a sub-micrometer glass pipette and their application as an intracellular selective ion sensor. Highly oriented, vertical and aligned ZnO nanorods were grown on the tip of a borosilicate glass capillary (0.7 µm in diameter) by the low temperature aqueous chemical growth (ACG) technique. The relatively large surface-to-volume ratio of ZnO nanorods makes them attractive for electrochemical sensing. Transmission electron microscopy studies show that ZnO nanorods are single crystals and grow along the crystal’s c-axis. The ZnO nanorods were functionalized with a polymeric membrane for selective intracellular measurements of Na+. The membrane-coated ZnO nanorods exhibited a Na+-dependent electrochemical potential difference versus an Ag/AgCl reference micro-electrode within a wide concentration range from 0.5 mM to 100 mM. The fabrication of functionalized ZnO nanorods paves the way to sense a wide range of biochemical species at the intracellular level.
Keywords: ZnO nanorods; HRTEM; functionalization; membrane; intracellular sensor ZnO nanorods; HRTEM; functionalization; membrane; intracellular sensor
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Asif, M.H.; Nur, O.; Willander, M.; Strålfors, P.; Brännmark, C.; Elinder, F.; Englund, U.H.; Lu, J.; Hultman, L. Growth and Structure of ZnO Nanorods on a Sub-Micrometer Glass Pipette and Their Application as Intracellular Potentiometric Selective Ion Sensors. Materials 2010, 3, 4657-4667.

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