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Advances in Porous Biomaterials for Dental and Orthopaedic Applications
Department of Mechanical Engineering, National Institute of Technology, Durgapur 713209, India
Biomechanics Section, Hamburg University of Technology, Hamburg D-21073, Germany
These authors contributed equally to this work and therefore share first authorship.
* Author to whom correspondence should be addressed.
Received: 5 February 2010; in revised form: 18 April 2010 / Accepted: 22 April 2010 / Published: 28 April 2010
Abstract: The connective hard tissues bone and teeth are highly porous on a micrometer scale, but show high values of compression strength at a relatively low weight. The fabrication of porous materials has been actively researched and different processes have been developed that vary in preparation complexity and also in the type of porous material that they produce. Methodologies are available for determination of pore properties. The purpose of the paper is to give an overview of these methods, the role of porosity in natural porous materials and the effect of pore properties on the living tissues. The minimum pore size required to allow the ingrowth of mineralized tissue seems to be in the order of 50 µm: larger pore sizes seem to improve speed and depth of penetration of mineralized tissues into the biomaterial, but on the other hand impair the mechanical properties. The optimal pore size is therefore dependent on the application and the used material.
Keywords: biomaterial; porosity; tissue engineering; bone; teeth
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MDPI and ACS Style
Mour, M.; Das, D.; Winkler, T.; Hoenig, E.; Mielke, G.; Morlock, M.M.; Schilling, A.F. Advances in Porous Biomaterials for Dental and Orthopaedic Applications. Materials 2010, 3, 2947-2974.
Mour M, Das D, Winkler T, Hoenig E, Mielke G, Morlock MM, Schilling AF. Advances in Porous Biomaterials for Dental and Orthopaedic Applications. Materials. 2010; 3(5):2947-2974.
Mour, Meenakshi; Das, Debarun; Winkler, Thomas; Hoenig, Elisa; Mielke, Gabriela; Morlock, Michael M.; Schilling, Arndt F. 2010. "Advances in Porous Biomaterials for Dental and Orthopaedic Applications." Materials 3, no. 5: 2947-2974.