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Materials 2010, 3(2), 755-763; doi:10.3390/ma3020755

Towards the Development of Electrical Biosensors Based on Nanostructured Porous Silicon

Departamento de Física Aplicada and Centro de Investigaciones Biomédicas en Red; Biomateriales, Bioingeniería y Nanomedicina (CIBERbbn), Universidad Autónoma de Madrid, 29049 Cantoblanco, Madrid, Spain
* Author to whom correspondence should be addressed.
Received: 14 December 2009 / Revised: 12 January 2010 / Accepted: 25 January 2010 / Published: 27 January 2010
(This article belongs to the Special Issue Porous Materials)
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The typical large specific surface area and high reactivity of nanostructured porous silicon (nanoPS) make this material very suitable for the development of sensors. Moreover, its biocompatibility and biodegradability opens the way to the development of biosensors. As such, in this work the use of nanoPS in the field of electrical biosensing is explored. More specifically, nanoPS-based devices with Al/nanoPS/Al and Au-NiCr/nanoPS/Au-NiCr structures were fabricated for the electrical detection of glucose and Escherichia Coli bacteria at different concentrations. The experimental results show that the current-voltage characteristics of these symmetric metal/nanoPS/metal structures strongly depend on the presence/absence and concentration of species immobilized on the surface.
Keywords: porous silicon; glucose; Escherichia coli; biosensing porous silicon; glucose; Escherichia coli; biosensing
This is an open access article distributed under the Creative Commons Attribution License (CC BY) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Recio-Sánchez, G.; Torres-Costa, V.; Manso, M.; Gallach, D.; López-García, J.; Martín-Palma, R.J. Towards the Development of Electrical Biosensors Based on Nanostructured Porous Silicon. Materials 2010, 3, 755-763.

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