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Materials 2009, 2(3), 719-733; doi:10.3390/ma2030719
Article

Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices

1,* , 1, 1,2, 1, 1 and 1
Received: 13 May 2009; Accepted: 18 June 2009 / Published: 30 June 2009
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Abstract: Polyurethane films have potential applications in medicine, especially for packaging implantable medical devices. Although polyether-urethanes have superior mechanical properties and are biocompatible, achieving water resistance is still a challenge. Polyether based polyurethanes with two different molecular weights (PTMO1000, PTMO2000) were prepared from 4,4’-diphenylmethane diisocyanate and poly(tetra-methylene oxide). Polymer films were introduced using different concentrations (0.5-10 wt %) of isopropyl myristate lipid (IPM) as a non-toxic modifying agent. The physical and mechanical properties of these polymers were characterised using physical and spectroscopy techniques (FTIR, Raman, DSC, DMA, tensile testing). Water contact angle and water uptake of the membranes as a function of IPM concentration was also determined accordingly. The FTIR and Raman data indicate that IPM is dispersed in polyurethane at ≤ 2wt% and thermal analysis confirmed this miscibility to be dependent on soft segment length. Modified polymers showed increased tensile strength and failure strain as well as reduced water uptake by up to 24% at 1-2 wt% IPM.
Keywords: polyether-urethane; isopropyl myristate; blend; physical properties polyether-urethane; isopropyl myristate; blend; physical properties
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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MDPI and ACS Style

Roohpour, N.; Wasikiewicz, J.M.; Moshaverinia, A.; Paul, D.; Rehman, I.U.; Vadgama, P. Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices. Materials 2009, 2, 719-733.

AMA Style

Roohpour N, Wasikiewicz JM, Moshaverinia A, Paul D, Rehman IU, Vadgama P. Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices. Materials. 2009; 2(3):719-733.

Chicago/Turabian Style

Roohpour, Nima; Wasikiewicz, Jaroslaw M.; Moshaverinia, Alireza; Paul, Deepen; Rehman, Ihtesham U.; Vadgama, Pankaj. 2009. "Isopropyl Myristate-Modified Polyether-Urethane Coatings as Protective Barriers for Implantable Medical Devices." Materials 2, no. 3: 719-733.


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