Next Article in Journal
A Photoluminescence Study of the Changes Induced in the Zinc White Pigment by Formation of Zinc Complexes
Next Article in Special Issue
Linear Graphene Nanocomposite Synthesis and an Analytical Application for the Amino Acid Detection of Camellia nitidissima Chi Seeds
Previous Article in Journal
A Series of Robust Copper-Based Triazolyl Isophthalate MOFs: Impact of Linker Functionalization on Gas Sorption and Catalytic Activity †
Article Menu
Issue 4 (April) cover image

Export Article

Open AccessCommunication
Materials 2017, 10(4), 336; doi:10.3390/ma10040336

Tracing the Bioavailability of Three-Dimensional Graphene Foam in Biological Tissues

1
College of Engineering, Mathematics and Physical Sciences, University of Exeter, Exeter EX4 4QF, UK
2
Department of Chemistry, Florida Institute of Technology, 150 W University Blvd, Melbourne, FL 3290, USA
3
Department of Zoology, Government College University, Faisalabad 3800, Pakistan
*
Author to whom correspondence should be addressed.
Academic Editor: Barbara Zavan
Received: 1 February 2017 / Revised: 8 March 2017 / Accepted: 21 March 2017 / Published: 24 March 2017
(This article belongs to the Special Issue Bioapplications of Graphene Composites)
View Full-Text   |   Download PDF [3483 KB, uploaded 24 March 2017]   |  

Abstract

Graphene-based materials with a three-dimensional (3D) framework have been investigated for a variety of biomedical applications because of their 3D morphology, excellent physiochemical properties, volume stability, and their controllable degradation rate. Current knowledge on the toxicological implications and bioavailability of graphene foam (GF) has major uncertainties surrounding the fate and behavior of GF in exposed environments. Bioavailability, uptake, and partitioning could have potential effects on the behavior of GF in living organisms, which has not yet been investigated. Here, we report a pilot toxicology study on 3D GF in common carps. Our results showed that GF did not show any noticeable toxicity in common carps, and the antioxidant enzymatic activities, biochemical and blood parameters persisted within the standard series. Further histological imaging revealed that GF remained within liver and kidney macrophages for 7 days without showing obvious toxicity. An in vivo study also demonstrated a direct interaction between GF and biological systems, verifying its eco-friendly nature and high biocompatibility. View Full-Text
Keywords: graphene foam; bioavailability; biological tissues; fish graphene foam; bioavailability; biological tissues; fish
Figures

Figure 1

This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. (CC BY 4.0).

Supplementary material

Scifeed alert for new publications

Never miss any articles matching your research from any publisher
  • Get alerts for new papers matching your research
  • Find out the new papers from selected authors
  • Updated daily for 49'000+ journals and 6000+ publishers
  • Define your Scifeed now

SciFeed Share & Cite This Article

MDPI and ACS Style

Tabish, T.A.; Chabi, S.; Ali, M.; Xia, Y.; Jabeen, F.; Zhang, S. Tracing the Bioavailability of Three-Dimensional Graphene Foam in Biological Tissues. Materials 2017, 10, 336.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Related Articles

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Materials EISSN 1996-1944 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top